DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12716 and TMEFF1

DIOPT Version :9

Sequence 1:	NP_572845.1	Gene:	CG12716 / 32248	FlyBaseID:	FBgn0030439	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_003683.2	Gene:	TMEFF1 / 8577	HGNCID:	11866	Length:	380	Species:	Homo sapiens

Alignment Length:	146	Identity:	31/146 - (21%)
Similarity:	52/146 - (35%)	Gaps:	47/146 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 GEAGLGQDADDKEHKGLGPMQIQY------VDYQPNCQPGGVPVCATNGTDSFYFENHCRLEAAN 118
            |..|.|.|....:.|.:...::..      |..:.:|:.|||                |:.:...
Human    46 GGGGSGGDCPGGKGKSINCSELNVRESDVRVCDESSCKYGGV----------------CKEDGDG 94

  Fly   119 MKMLFQHGTELEPTEMERCLPNCQTMKCTQVERPVCALAEIGGAIPQTFANECEMRKHECHTKQV 183
            :|                |.  || .:|.....|||      |:...|:.|||.:|:..|..::.
Human    95 LK----------------CA--CQ-FQCHTNYIPVC------GSNGDTYQNECFLRRAACKHQKE 134

  Fly   184 LRILHTGPCQTPTKSG 199
            :.::..|||.:...||
Human   135 ITVIARGPCYSDNGSG 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12716	NP_572845.1	KAZAL_FS	146..192	CDD:238052	12/45 (27%)
TMEFF1	NP_003683.2	KAZAL	99..143	CDD:197624	14/50 (28%)
		KAZAL	189..235	CDD:197624
		PHA02887	<275..311	CDD:333467
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	359..380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900