Protein Alignment hec and VIPR2

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_005249618.1
• Gene: VIPR2 / 7434
• HGNCID: 12695
• Length: 463
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 114/450 - (25%)
• Similarity: 205/450 - (45%)
• Gaps: 60/450 - (13%)

  Fly    50 PSFSLGPATDYDSDLPENFSPVPRY-LENAAMNEGVIDMRNVDEELAEKEELMATVVSATMATNQ 113
            |...|||:...   |..:..|..|: ||             :.||..:..||:         .:|
Human    31 PQMPLGPSLYL---LVNSIHPECRFHLE-------------IQEEETKCAELL---------RSQ 70

  Fly   114 KENRLFCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKF-LAHKTCLENGSWYRHPVSNQTWS 177
            .|....|...:|...||.....|..::..||.....|..|. ...|.|..:| |      ::|:.
Human    71 TEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETFP 128

  Fly   178 NYTNCVDYEDLE------FRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFAS 236
            ::.:...|.|.|      |...:..:|..||::||::|....||...|:.|.|||..||::||.|
Human   129 DFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLS 193

  Fly   237 LACTCVAWILWYRLVVERSETI--AENPLWCIG--LHLV-VHYFMLVNYFWMFCEGLHLHLVLVV 296
            .....::.::...::...|.|:  .:.|...:|  |.|| :.|.::.|:||:..|||:||.:||.
Human   194 FILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVA 258

  Fly   297 VFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCWITD--SLYLWIFSVPITLSLLAS 359
            :.......:. :::|.|..|......:..||.:.  ::..||.|:  |:..|:..:||.:|::.:
Human   259 MLPPRRCFLA-YLLIGWGLPTVCIGAWTAARLYL--EDTGCWDTNDHSVPWWVIRIPILISIIVN 320

  Fly   360 FIFLINVLRVIVRKL-HPQSAQPAPLAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLDHFYQM 423
            |:..|:::|::::|| .|..........::..::|::|:||||:.:.:....|   ..:...||:
Human   321 FVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP---ISISSKYQI 382

  Fly   424 L-SVVLVSLQGFVVSFLFCFANHDVTFAIRTLLNKLLPSLVTPPPAGSNTGQMATTTPSR 482
            | .:.|.|.||.||:.|:||.|.:|...::.......|:     |:.|...::..::.||
Human   383 LFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPT-----PSASRDYRVCGSSFSR 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	14/67 (21%)
		7tm_4	216..436	CDD:304433	61/228 (27%)
VIPR2	XP_005249618.1	HormR	77..143	CDD:214468	17/72 (24%)
		7tm_2	148..396	CDD:278432	69/253 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810