Protein Alignment hec and VIPR1

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_004615.2
• Gene: VIPR1 / 7433
• HGNCID: 12694
• Length: 457
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 126/469 - (26%)
• Similarity: 215/469 - (45%)
• Gaps: 91/469 - (19%)

  Fly    51 SFSLGPATDYDSDLPENFSPVPRYLENAAMNEGVIDMRNVDEELAEKEELMATVVSATMATNQKE 115
            :::||||....:.|.|...    |::       :|::::  ::..|:.:|              |
Human    20 AWALGPAGGQAARLQEECD----YVQ-------MIEVQH--KQCLEEAQL--------------E 57

  Fly   116 NR-LFCPLNFDGYLCWPRTPAGTVLSQYCP------DFVEGFNRKFLAHKTCLENGSWYR----- 168
            |. :.|...:|...|||.||.|.|:...||      ..::|.|    ..::|.:.| |..
Human    58 NETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRN----VSRSCTDEG-WTHLEPGP 117

  Fly   169 HPVSNQTWSNYTNC--------VDYEDLEFRQFINELYVKGYALSLLALLISIIIFLGFKSLRCT 225
            :|::         |        :|.:...|...:...|..||.|||..||::..|...|:.|.||
Human   118 YPIA---------CGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCT 173

  Fly   226 RIRIHVHLFASLACTCVAWILWYRLVVE--RSETIAENPLWCIGLHLVVHYFMLVNYFWMFCEGL 288
            |..||:|||.|......|..:....:.:  .|:..:|..:.|....:...|.::.|:||:..|||
Human   174 RNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGL 238

  Fly   289 HLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLAR-HFSSPDNKHCW--ITDSLYLWIFSV 350
            :|:.:|.|.|..:......:|:|.|..|....:|:.:|| ||   ::..||  |..||: ||...
Human   239 YLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHF---EDYGCWDTINSSLW-WIIKG 299

  Fly   351 PITLSLLASFIFLINVLRVIVRKLHP---QSAQPAPLAIRKAVRATIILVPLFGLQHFLLPYRPD 412
            ||..|:|.:||..|.::|::::||.|   :.:..:|.:  :..|:|::|:||||:.:.:..:.|
Human   300 PILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYS--RLARSTLLLIPLFGVHYIMFAFFP- 361

  Fly   413 AGTQLDHF----YQMLSVVLVSLQGFVVSFLFCFANHDVTFAIRTLLNK--LLPSLVTPP----P 467
                 |:|    ..:..:|:.|.|||||:.|:||.|.:|...:|....:  |...|...|    |
Human   362 -----DNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHP 421

  Fly   468 AGSNTGQMATTTPS 481
            :|.:.|...:|..|
Human   422 SGGSNGATCSTQVS 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	18/85 (21%)
		7tm_4	216..436	CDD:304433	69/231 (30%)
VIPR1	NP_004615.2	HormR	59..128	CDD:214468	18/82 (22%)
		7tm_2	139..384	CDD:278432	78/256 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810