Protein Alignment hec and SCTR

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_011509923.1
• Gene: SCTR / 6344
• HGNCID: 10608
• Length: 445
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 99/359 - (27%)
• Similarity: 176/359 - (49%)
• Gaps: 45/359 - (12%)

  Fly   120 CPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNY----- 179
            |...:|...|||.:..|.::...||.|:.....:         |||.:|: .:...||..
Human    66 CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSR---------NGSLFRN-CTQDGWSETFPRPN 120

  Fly   180 ----TNCVDYEDLEFRQFINEL---YVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASL 237
                .|..|..:.:...::.:|   |..||:.||:.||:::.|...|:.|.|||..||:|||.|.
Human   121 LACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSF 185

  Fly   238 ACTCVAWILWYRLVVERSETIAENPLWC----IGLHLVV---HYFMLVNYFWMFCEGLHLHLVLV 295
            ....::     ..:.:.....:::..:|    .|..||:   .|.::.||.|:..|||:||.:|.
Human   186 ILRALS-----NFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLA 245

  Fly   296 VVFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSP---DNKHCW---ITDSLYLWIFSVPITL 354
            :.|..:...::.|:...|.||.....::.:||||...   .:..||   ...|:: ||...|:.|
Human   246 ISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCPSLRCWDINANASIW-WIIRGPVIL 309

  Fly   355 SLLASFIFLINVLRVIVRKLHPQSAQPAPLA-IRKAVRATIILVPLFGLQHFLLPYRPDAGTQLD 418
            |:|.:||..||:||:::|||..|..:...:: .::..|:|::|:||||:.:.:..:.|:...::.
Human   310 SILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQ 374

  Fly   419 HFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR 452
            .|:::   .|.|.||.||:.|:||.|.:|...::
Human   375 LFFEL---ALGSFQGLVVAVLYCFLNGEVQLEVQ 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	16/73 (22%)
		7tm_4	216..436	CDD:304433	66/233 (28%)
SCTR	XP_011509923.1	HRM	64..126	CDD:280888	15/69 (22%)
		7tm_2	139..389	CDD:278432	75/258 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810