Protein Alignment hec and Crhr1

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_112261.1
• Gene: Crhr1 / 58959
• RGDID: 61276
• Length: 415
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 122/378 - (32%)
• Similarity: 188/378 - (49%)
• Gaps: 53/378 - (14%)

  Fly   105 VSATMATNQKENRLFCPLNFDGY----------LCWPRTPAGTVLSQYCPDFVEG--FNRKFLAH 157
            ||.::...:.|| |....|..|.          .||||:|||.::.:.||.|..|  :|.....:
  Rat    21 VSTSLQDQRCEN-LSLTSNVSGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGY 84

  Fly   158 KTCLENGSWYRHPVSNQTWSNYTNCVDYEDLEFRQ--------FINELYVKGYALSLLALLISII 214
            :.||.||||...       .||:.|.:..:.|.:.        .||.|   |:.:||:|||::.:
  Rat    85 RECLANGSWAAR-------VNYSECQEILNEEKKSKVHYHVAVIINYL---GHCISLVALLVAFV 139

  Fly   215 IFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENPLWCIGLHLVVHYFMLVN 279
            :||..:|:||.|..||.:|.::.......|.: .:|.|. .|....|..||..:....:||.:.|
  Rat   140 LFLRLRSIRCLRNIIHWNLISAFILRNATWFV-VQLTVS-PEVHQSNVAWCRLVTAAYNYFHVTN 202

  Fly   280 YFWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLAR-HFSSPDNKHCWI---- 339
            :||||.||.:||..:|:.:..|.:....|:.|.|..|.||.:.:.:.: |:   ||:.||.
  Rat   203 FFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPFPIIVAWAIGKLHY---DNEKCWFGKRP 264

  Fly   340 ---TDSLYLWIFSVPITLSLLASFIFLINVLRVIVRKLHPQSAQPAPLAIRKAVRATIILVPLFG 401
               ||    :|:..|:.|.||.:||||.|::|:::.||. .|.....:..||||:||::|:||.|
  Rat   265 GVYTD----YIYQGPMILVLLINFIFLFNIVRILMTKLR-ASTTSETIQYRKAVKATLVLLPLLG 324

  Fly   402 LQHFLLPYRP--DAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR 452
            :.:.|....|  |..:::...|  .:..|.|.|||.||..:||.|.:|..|||
  Rat   325 ITYMLFFVNPGEDEVSRVVFIY--FNSFLESFQGFFVSVFYCFLNSEVRSAIR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	24/78 (31%)
		7tm_4	216..436	CDD:304433	75/229 (33%)
Crhr1	NP_112261.1	HormR	40..111	CDD:214468	23/77 (30%)
		Important for peptide agonist binding. /evidence=ECO:0000250	99..108		2/8 (25%)
		7tm_2	116..359	CDD:278432	84/257 (33%)
		Important for antagonist binding. /evidence=ECO:0000250	280..290		6/9 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810