Protein Alignment hec and PTH1R

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_011532269.1
• Gene: PTH1R / 5745
• HGNCID: 9608
• Length: 606
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 118/370 - (31%)
• Similarity: 188/370 - (50%)
• Gaps: 43/370 - (11%)

  Fly   120 CPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNYTNCVD 184
            |...:|..||||....|.|::..|||::..||.|..|::.|..||||...|..|:||:||:.||.
Human   121 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVK 185

  Fly   185 YEDLEFRQ-----FINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVA- 243
            :...|.|:     .:..:|..||::||.:|.::::|...|:.|.|||..||:|||.|.....|:
Human   186 FLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSI 250

  Fly   244 ----WILWYRLVVERSETIAENPLWCI---------------GLHLVVH---YFMLVNYFWMFCE 286
                .:|:....::.:|.:.|..|..|               |..:.|.   ||:..||:|:..|
Human   251 FVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVE 315

  Fly   287 GLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCW-ITDSLYLWIFSV 350
            ||:||.::.:.|..:...:..|.|..|..|.....|:...|  ::..|..|| ::.....||..|
Human   316 GLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVR--ATLANTGCWDLSSGNKKWIIQV 378

  Fly   351 PITLSLLASFIFLINVLRVIVRKLHPQSAQPAPL--AIRKAVRATIILVPLFGLQHFLL----PY 409
            ||..|::.:||..||::||:..||...:|.....  ..||.:::|::|:||||: |:::    ||
Human   379 PILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGV-HYIVFMATPY 442

  Fly   410 RPDAGT--QLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR 452
            ...:||  |:...|:||   ..|.|||.|:.::||.|.:|...|:
Human   443 TEVSGTLWQVQMHYEML---FNSFQGFFVAIIYCFCNGEVQAEIK 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	28/64 (44%)
		7tm_4	216..436	CDD:304433	75/251 (30%)
PTH1R	XP_011532269.1	HRM	118..186	CDD:280888	28/64 (44%)
		7tm_2	197..468	CDD:278432	82/276 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910