Sequence 1: | NP_001285174.1 | Gene: | hec / 32246 | FlyBaseID: | FBgn0030437 | Length: | 486 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000151.1 | Gene: | GCGR / 2642 | HGNCID: | 4192 | Length: | 477 | Species: | Homo sapiens |
Alignment Length: | 429 | Identity: | 119/429 - (27%) |
---|---|---|---|
Similarity: | 200/429 - (46%) | Gaps: | 50/429 - (11%) |
- Green bases have known domain annotations that are detailed below.
Fly 94 LAEKEELMATVVSATMATNQKENRLFCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNR---KFL 155
Fly 156 AHKTCLENGSWYRHPVSNQTWSNYTNC-VDYEDLEFRQFINE-------LYVKGYALSLLALLIS 212
Fly 213 IIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVER-SETIAEN---PLW--------C 265
Fly 266 IGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSP----IPIAIVYGLA 326
Fly 327 RHFSSPDNKHCWIT-DSL-YLWIFSVPITLSLLASFIFLINVLRVIVRKLHPQSAQPAPLAIRKA 389
Fly 390 VRATIILVPLFGLQHFLLPYRPDAGTQ--LDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR 452
Fly 453 T-----LLNKLL--PSLVTPPPAGSNTGQMATTTPSREL 484 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
hec | NP_001285174.1 | HRM | 118..185 | CDD:280888 | 24/70 (34%) |
7tm_4 | 216..436 | CDD:304433 | 61/239 (26%) | ||
GCGR | NP_000151.1 | HRM | 55..122 | CDD:308439 | 23/68 (34%) |
7tmB1_GCGR | 136..410 | CDD:320395 | 77/280 (28%) | ||
TM helix 1 | 140..165 | CDD:320395 | 10/24 (42%) | ||
TM helix 2 | 174..196 | CDD:320395 | 6/21 (29%) | ||
TM helix 3 | 225..252 | CDD:320395 | 9/26 (35%) | ||
TM helix 4 | 264..284 | CDD:320395 | 4/19 (21%) | ||
TM helix 5 | 300..329 | CDD:320395 | 6/28 (21%) | ||
TM helix 6 | 345..370 | CDD:320395 | 7/25 (28%) | ||
Allosteric inhibitor binding. /evidence=ECO:0000269|PubMed:27111510, ECO:0000269|PubMed:28514451 | 350..353 | 1/2 (50%) | |||
TM helix 7 | 379..404 | CDD:320395 | 8/24 (33%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 431..477 | 7/21 (33%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG4564 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 1 | 1.000 | - | - | X66 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |