Protein Alignment hec and Adcyap1r1

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001257508.1
• Gene: Adcyap1r1 / 24167
• RGDID: 2038
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 462
• Identity: 107/462 - (23%)
• Similarity: 188/462 - (40%)
• Gaps: 126/462 - (27%)

  Fly    96 EKEELMATVVSATMATNQKENRLF--------CPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFN- 151
            :||:.|.      :...|:.|.|.        ||..:|...||.....|.::...||:....||
  Rat    27 KKEQAMC------LERIQRANDLMGLNESSPGCPGMWDNITCWKPAQVGEMVLVSCPEVFRIFNP 85

  Fly   152 -----------------------RKFLAHKTCLENGSWYRHPVSNQTWSNYTNCVDYEDLE---- 189
                                   ...:..:.|.|:| |      ::.:.:|.:...::|.|
  Rat    86 DQVWMTETIGDSGFADSNSLEITDMGVVGRNCTEDG-W------SEPFPHYFDACGFDDYEPESG 143

  Fly   190 ----FRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVA-----WI 245
                :...:..||..||:.||..|..:::|...|:.|.|||..||::||.|.....::     ||
  Rat   144 DQDYYYLSVKALYTVGYSTSLATLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWI 208

  Fly   246 LWYRLVVERSETIAENPLWCIGLHLVVHYFMLVNYFWMFCEGLHLHLVLVVVFVKDTIVMRWFIV 310
            |:   ..:.|.....:.:.|..:.:..||.::.||||:|.|||:|..:||..|..:.....|:.:
  Rat   209 LY---AEQDSSHCFVSTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTI 270

  Fly   311 ISWFSPIPIAIVYGLARHFSSPDNKHCW-ITDSLYL-WIFSVPITLSLLASFIFLINVLRVIVRK 373
            |.|.:|.....|:.:.|.:.  |:..|| :.||..| |:...|:..|::.:|:..|.::.::|:|
  Rat   271 IGWGTPTVCVTVWAVLRLYF--DDAGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIIILVQK 333

  Fly   374 LH--------------------------------------------------PQSAQP------- 381
            |.                                                  ||.||.
  Rat   334 LQSPDMGGNESSIYLTNLRLRVPKKTREDPLPVPSDQHSPPFLSCVQKCYCKPQRAQQHSCKMSE 398

  Fly   382 -APLAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANH 445
             :.:.:|.| |:|::|:||||:.:.:..:.|:..::.:..  :..:.|.|.|||||:.|:||.|.
  Rat   399 LSTITLRLA-RSTLLLIPLFGIHYTVFAFSPENVSKRERL--VFELGLGSFQGFVVAVLYCFLNG 460

  Fly   446 DVTFAIR 452
            :|...|:
  Rat   461 EVQAEIK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	16/98 (16%)
		7tm_4	216..436	CDD:304433	68/284 (24%)
Adcyap1r1	NP_001257508.1	HRM	51..136	CDD:280888	15/91 (16%)
		Important for ligand binding and specificity. /evidence=ECO:0000250	124..138		1/13 (8%)
		7tm_2	149..451	CDD:278432	76/309 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810