DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hec and anmt-2

DIOPT Version :9

Sequence 1:	NP_001285174.1	Gene:	hec / 32246	FlyBaseID:	FBgn0030437	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_498334.1	Gene:	anmt-2 / 175868	WormBaseID:	WBGene00018340	Length:	274	Species:	Caenorhabditis elegans

Alignment Length:	172	Identity:	39/172 - (22%)
Similarity:	59/172 - (34%)	Gaps:	63/172 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DPSFSLGPATDYDSDLPEN----FSP---VPRYLENAAMNEGVIDMRNVDEELAEKEELMATVVS 106
            ||:.:......:...|||:    |.|   :..|....|:.:|.            :..|.|..|.
Worm     6 DPTITESSDAQHTVLLPEDYVKKFDPDEYLQFYFSRDAIEDGT------------RVSLFALPVF 58

  Fly   107 A-----TMATNQKENRLFCPLNFDGYLCWPRTPAG-TVLSQYC----------PDFVE---GFNR 152
            |     ||..:::|..|             ...|| ||.|..|          .|||:   ...|
Worm    59 AQLMLQTMRPSERETLL-------------DIGAGPTVYSALCFRDVAKRVHLSDFVDRNLDVLR 110

  Fly   153 KFLAHKTCLENGSWYRHP---VSNQTWSNYTN----CVDYED 187
            |::.|:..::   |.  |   |.|:|....|.    |:|.|:
Worm   111 KWIRHEETID---WV--PTIKVINRTEGGPTPTDQVCIDVEE 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	20/87 (23%)
hec	NP_001285174.1	7tm_4	216..436	CDD:304433
anmt-2	NP_498334.1	NNMT_PNMT_TEMT	13..273	CDD:250464	37/165 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900