DRSC/TRiP Functional Genomics Resources

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Protein Alignment hec and Ghrhr

DIOPT Version :10

Sequence 1:NP_572843.2 Gene:hec / 32246 FlyBaseID:FBgn0030437 Length:486 Species:Drosophila melanogaster
Sequence 2:XP_036021736.1 Gene:Ghrhr / 14602 MGIID:95710 Length:444 Species:Mus musculus


Alignment Length:122 Identity:27/122 - (22%)
Similarity:43/122 - (35%) Gaps:49/122 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 TEMAVVW-----NTFSEVSQ--DVTYGKTG------------SGA----TSTAK----------- 32
            ||:::::     .|.:|:.|  |:.||:.|            ||.    .:|.|           
Mouse   165 TELSIIYKYSPFKTEAELMQQFDMIYGRCGTLLIIYNLKLLLSGEPELDVTTDKEDILMAEALEE 229

  Fly    33 ----GSSEAW-----------VFGGITRYRHKAIMTGLEYSTEYDYTIASRKFSFKT 74
                .|..|:           :|....|.:.|.:...|....:|.||.:|.|..|||
Mouse   230 FPERRSFRAYTAVLYFEPRMRIFIQAKRVQTKHLCYSLYKPRKYQYTTSSFKGKFKT 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hecNP_572843.2 HRM 118..183 CDD:397086
7tmB1_NPR_B4_insect-like 191..457 CDD:320388
TM helix 1 193..218 CDD:320388
TM helix 2 227..249 CDD:320388
TM helix 3 266..293 CDD:320388
TM helix 4 305..325 CDD:320388
TM helix 5 341..370 CDD:320388
TM helix 6 385..412 CDD:320388
TM helix 7 419..444 CDD:320388
GhrhrXP_036021736.1 HRM 53..112 CDD:397086
7tm_GPCRs 126..>325 CDD:475119 27/122 (22%)
TM helix 1 129..153 CDD:410628
TM helix 2 162..183 CDD:410628 4/17 (24%)
TM helix 3 203..225 CDD:410628 4/21 (19%)
TM helix 4 244..260 CDD:410628 2/15 (13%)
TM helix 5 278..301 CDD:410628 5/9 (56%)
Blue background indicates that the domain is not in the aligned region.

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