Protein Alignment hec and CRHR2

DIOPT Version :9

• Sequence 1: NP_001285174.1
• Gene: hec / 32246
• FlyBaseID: FBgn0030437
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001189404.1
• Gene: CRHR2 / 1395
• HGNCID: 2358
• Length: 438
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 113/372 - (30%)
• Similarity: 193/372 - (51%)
• Gaps: 38/372 - (10%)

  Fly    98 EELMATVVSATMATNQKENRLFCPLNFDGY-LCWPRTPAGTVLSQYCPDFVEG--FNRKFLAHKT 159
            |:...|:::   .||......:|....|.. .||||:.||.::.:.||::..|  :|....|::.
Human    48 EQYCHTIMT---LTNLSGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRE 109

  Fly   160 CLENGSWYRHPVSNQTWSNYTNCVDYEDLEFRQF---------INELYVKGYALSLLALLISIII 215
            |||||:|       .:..||:.|....|.:.|::         :|.|   |:.:|:.||:.:.::
Human   110 CLENGTW-------ASKINYSQCEPILDDKQRKYDLHYRIALVVNYL---GHCVSVAALVAAFLL 164

  Fly   216 FLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENPLWCIGLHLVVHYFMLVNY 280
            ||..:|:||.|..||.:|..:.   .:..::|:.|.:...|....|.:||..:..:.:||::.|:
Human   165 FLALRSIRCLRNVIHWNLITTF---ILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNF 226

  Fly   281 FWMFCEGLHLHLVLVVVFVKDTIVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCWI---TDS 342
            ||||.||.:||..:|:.:..:.:....|:.|.|..|.||.:.:.:.:.:.  :|:.||.   ...
Human   227 FWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYY--ENEQCWFGKEPGD 289

  Fly   343 LYLWIFSVPITLSLLASFIFLINVLRVIVRKLHPQSAQPAPLAIRKAVRATIILVPLFGLQHFLL 407
            |..:|:..||.|.||.:|:||.|::|:::.||. .|.....:..||||:||::|:||.|:.:.|.
Human   290 LVDYIYQGPIILVLLINFVFLFNIVRILMTKLR-ASTTSETIQYRKAVKATLVLLPLLGITYMLF 353

  Fly   408 PYRP--DAGTQLDHFYQMLSVVLVSLQGFVVSFLFCFANHDVTFAIR 452
            ...|  |..:|:...|  .:..|.|.|||.||..:||.|.:|..|:|
Human   354 FVNPGEDDLSQIMFIY--FNSFLQSFQGFFVSVFYCFFNGEVRSAVR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hec	NP_001285174.1	HRM	118..185	CDD:280888	22/69 (32%)
		7tm_4	216..436	CDD:304433	71/224 (32%)
CRHR2	NP_001189404.1	HormR	63..134	CDD:214468	23/77 (30%)
		7tm_2	140..382	CDD:278432	77/252 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X66
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810