DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fne and hfp

DIOPT Version :9

Sequence 1:	NP_001096965.1	Gene:	fne / 32245	FlyBaseID:	FBgn0086675	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_525123.2	Gene:	hfp / 38173	FlyBaseID:	FBgn0028577	Length:	637	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	64/256 - (25%)
Similarity:	101/256 - (39%)	Gaps:	77/256 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 MTQEEMRSLFSSIGELESCKLVRDKVSGNLVLPASLTALNPALQQGQSLGYGFVNYVRAEDAEKA 101
            :.::.:|..|:..|.::|..:..|                |..|:.:  |:.||.|...|.|:.|
  Fly   141 LKEDTIRVAFTPFGPIKSINMSWD----------------PITQKHK--GFAFVEYEIPEGAQLA 187

  Fly   102 VNTLNGLRLQNKVIKVSYARPSS------------ESIKGAN-LYVSGLPKNLSQPDLEGMFASF 153
            :..:||..:..:.|||  .|||:            |..|..| :||:.:..:||:.|::.:|.:|
  Fly   188 LEQMNGALMGGRNIKV--GRPSNMPQAQQVIDEVQEEAKSFNRIYVASIHPDLSEEDIKSVFEAF 250

  Fly   154 GKIITSRILCDNISGLS----KGVGFIRFDQRNEAERAIQELN-----------GKT---PKGYA 200
            |.|    :.|....|.|    ||.|||.:..:...:.||..:|           |::   |...|
  Fly   251 GPI----LYCKLAQGTSLHTHKGYGFIEYANKQAMDEAIASMNLFDLGGQLLRVGRSITPPNALA 311

  Fly   201 EPITVKFANNPSNSAKAQIAPPLTAYL-----------------TP-QAAAATRRLAGALP 243
            .|.|    |:...:|.|..|...||.:                 || .||.|.....||:|
  Fly   312 CPTT----NSTMPTAAAVAAAAATAKIQALDAVASNAVLGLSQNTPVMAAGAVVTKVGAMP 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fne	NP_001096965.1	ELAV_HUD_SF	23..354	CDD:273741	64/256 (25%)
hfp	NP_525123.2	half-pint	10..637	CDD:130706	64/256 (25%)
		RRM1_PUF60	130..205	CDD:240816	19/83 (23%)
		RRM2_PUF60	227..303	CDD:240817	22/79 (28%)
		RRM3_UHM_PUF60	536..636	CDD:241092
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439572
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840