Protein Alignment fne and ELAVL3

DIOPT Version :9

• Sequence 1: NP_001096965.1
• Gene: fne / 32245
• FlyBaseID: FBgn0086675
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_024307178.1
• Gene: ELAVL3 / 1995
• HGNCID: 3314
• Length: 424
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 214/424 - (50%)
• Similarity: 256/424 - (60%)
• Gaps: 108/424 - (25%)

  Fly    10 NGSANGSVDGSNDESRTNLIVNYLPQTMTQEEMRSLFSSIGELESCKLVRDKVSGNLVLPASLTA 74
            ||...|: :|:.|:|:||||||||||.|||:|.:|||.|||::|||||||||::
Human    24 NGPLLGT-NGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKIT----------- 76

  Fly    75 LNPALQQGQSLGYGFVNYVRAEDAEKAVNTLNGLRLQNKVIKVSYARPSSESIKGANLYVSGLPK 139
                   |||||||||||....||:||:||||||:||.|.||||||||||.||:.||||||||||
Human    77 -------GQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPK 134

  Fly   140 NLSQPDLEGMFASFGKIITSRILCDNI-------------------------------------- 166
            .:||.::|.:|:.:|:|||||||.|.:
Human   135 TMSQKEMEQLFSQYGRIITSRILVDQVTGQAVREGAPGGGAGQRQSGGTNVGKPTKMPGHEAGKG 199

  Fly   167 -------------------SGLSKGVGFIRFDQRNEAERAIQELNGKTPKGYAEPITVKFANNPS 212
                               :|:|:||||||||:|.|||.||:.|||:.|.|.|||||||||||||
Human   200 EVGLHRRGQGRRDGHPCPLAGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPS 264

  Fly   213 NSAKAQIAPPLTAYLTPQAAAATRRLAGAL---------------------PSAGRIRYSPLAGD 256
            ....       .|.||....::.||.||.|                     |.:...|:||:|.|
Human   265 QKTG-------QALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAID 322

  Fly   257 ---LLANSILPGNAMTGSGWCIFVYNLAPETEENVLWQLFGPFGAVQSVKVIRDLQTSKCKGFGF 318
               .||...|.|.| .|:|||||||||:||.:|:||||||||||||.:||||||..|:|||||||
Human   323 GMSGLAGVGLSGGA-AGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGF 386

  Fly   319 VTMTNYDEAVVAIQSLNGYTLGNRVLQVSFKTNK 352
            |||||||||.:||.|||||.||.|||||||||:|
Human   387 VTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSK 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fne	NP_001096965.1	ELAV_HUD_SF	23..354	CDD:273741	209/411 (51%)
ELAVL3	XP_024307178.1	RRM	36..423	CDD:330708	209/411 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5685
eggNOG	1	0.900	-	-		E1_KOG0145
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	419	1.000	Inparanoid score	I1806
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55893
OrthoDB	1	1.010	-	-		D425303at33208
OrthoFinder	1	1.000	-	-		FOG0000313
OrthoInspector	1	1.000	-	-		mtm8515
orthoMCL	1	0.900	-	-		OOG6_103306
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3804
SonicParanoid	1	1.000	-	-		X326
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870