Protein Alignment fne and ELAVL1

DIOPT Version :10

• Sequence 1: NP_001401058.1
• Gene: fne / 32245
• FlyBaseID: FBgn0086675
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: XP_047294339.1
• Gene: ELAVL1 / 1994
• HGNCID: 3312
• Length: 353
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 208/367 - (56%)
• Similarity: 255/367 - (69%)
• Gaps: 45/367 - (12%)

  Fly     8 VKNGSANG-----SVDGSNDESRTNLIVNYLPQTMTQEEMRSLFSSIGELESCKLVRDKVSGNLV 67
            :||..:||     :.|...|..|||||||||||.|||:|:|||||||||:||.||:||||:|:
Human    24 LKNTMSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGH-- 86

  Fly    68 LPASLTALNPALQQGQSLGYGFVNYVRAEDAEKAVNTLNGLRLQNKVIKVSYARPSSESIKGANL 132
                            ||||||||||.|:|||:|:|||||||||:|.|||||||||||.||.|||
Human    87 ----------------SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANL 135

  Fly   133 YVSGLPKNLSQPDLEGMFASFGKIITSRILCDNISGLSKGVGFIRFDQRNEAERAIQELNGKTPK 197
            |:||||:.::|.|:|.||:.||:||.||:|.|..:|||:||.|||||:|:|||.||...||..|.
Human   136 YISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPP 200

  Fly   198 GYAEPITVKFANNPSNSAKAQIAPPLTAYLTPQAAAATRRLAGAL-PSAGRISIGKSPMLAINKG 261
            |.:||||||||.||:.:....:...|  |.:|     .||..|.: ..|.|...  |||     |
Human   201 GSSEPITVKFAANPNQNKNVALLSQL--YHSP-----ARRFGGPVHHQAQRFRF--SPM-----G 251

  Fly   262 LQRYSPLAGDLLANSILPGNAMTGSGWCIFVYNLAPETEENVLWQLFGPFGAVQSVKVIRDLQTS 326
            :...|.|:|   .|  :||||  .||||||:|||..:.:|.:|||:|||||||.:||||||..|:
Human   252 VDHMSGLSG---VN--VPGNA--SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTN 309

  Fly   327 KCKGFGFVTMTNYDEAVVAIQSLNGYTLGNRVLQVSFKTNKT 368
            |||||||||||||:||.:||.|||||.||:::|||||||||:
Human   310 KCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKS 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fne	NP_001401058.1	ELAV_HUD_SF	23..369	CDD:273741	202/347 (58%)
ELAVL1	XP_047294339.1	ELAV_HUD_SF	46..353	CDD:273741	202/345 (59%)