DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4645 and yipf2

DIOPT Version :9

Sequence 1:	NP_001285171.1	Gene:	CG4645 / 32244	FlyBaseID:	FBgn0030435	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001003500.1	Gene:	yipf2 / 445106	ZFINID:	ZDB-GENE-040724-124	Length:	304	Species:	Danio rerio

Alignment Length:	286	Identity:	114/286 - (39%)
Similarity:	166/286 - (58%)	Gaps:	34/286 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SSAQGFSGAASSG----------GSQPQNSSLDGSAGGGGGGAKLSLFTIEYYQQFFNVDTYMVL 125
            ||:...:.||.||          .:|.::|.|.|.....||     .:|.||||.||||||..||
Zfish    31 SSSNPAAAAAPSGEVRLDLSDDEENQQESSELLGGEKKTGG-----FWTFEYYQSFFNVDTVQVL 90

  Fly   126 ERIANSMIPKRASGNYLRMNIGENPDLYGPFWITVTLIFSIAISGNIASYLQQATDAYKWHY--N 188
            :||..|::| ....|:::.:|..||||||||||.|||:||:|||||::::|.:..:. ::||  .
Zfish    91 DRIKGSVMP-LPGRNFIKHHIRSNPDLYGPFWICVTLVFSLAISGNLSTFLSEMGNP-EYHYRPQ 153

  Fly   189 FHLVSYAATSIFLYANILPAVLWALFKYSLKPVDSADAVETDSASYMPSLLSLMCIYGYSLAIYI 253
            ||.||.||.::||||.::|..:|....:       ..:||.....|  :.|..:|:|||||.|||
Zfish   154 FHRVSIAAVTVFLYAWLVPLGVWGFLTW-------RQSVERQINGY--TFLETVCVYGYSLFIYI 209

  Fly   254 PVSILWVINISLLQWLLVITAALLSGTVLIAVLTPALR-NSQFSLFLIVGILSA-HVVLAAGFLL 316
            |.|:||.|..:.|||||::.|.::||:||:....||:| :::.:.|..|.::.| |.:||.|..|
Zfish   210 PTSVLWTIPFNWLQWLLIVVAMVISGSVLVITFWPAVRDDTKLTAFATVAVIVALHALLAVGCKL 274

  Fly   317 YFFHNPTVPSLDPVAPTPAAPAAPAA 342
            ||||.    :.|..:|.|.....||:
Zfish   275 YFFHT----AEDTRSPHPGQHITPAS 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4645	NP_001285171.1	Yip1	149..310	CDD:282716	70/164 (43%)
yipf2	NP_001003500.1	Yip1	103..264	CDD:309843	70/170 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594369
Domainoid	1	1.000	153	1.000	Domainoid score	I4259
eggNOG	1	0.900	-	-		E1_KOG3114
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3882
OMA	1	1.010	-	-		QHG54497
OrthoDB	1	1.010	-	-		D1425332at2759
OrthoFinder	1	1.000	-	-		FOG0001880
OrthoInspector	1	1.000	-	-		otm26245
orthoMCL	1	0.900	-	-		OOG6_101326
Panther	1	1.100	-	-	LDO	PTHR12822
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1890
SonicParanoid	1	1.000	-	-		X1411
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800