DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4645 and Yipf2

DIOPT Version :9

Sequence 1:	NP_001285171.1	Gene:	CG4645 / 32244	FlyBaseID:	FBgn0030435	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001014230.1	Gene:	Yipf2 / 363027	RGDID:	1307512	Length:	311	Species:	Rattus norvegicus

Alignment Length:	305	Identity:	103/305 - (33%)
Similarity:	145/305 - (47%)	Gaps:	56/305 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VGGG-GANAQRQRGDPLADLIYDMTSSAQGFSGAASSGGSQPQNSSLDGSAGGGGGGAKLSLFTI 110
            ||.| |..|:.:..|....|:.|                .:||.                ..:|.
  Rat    44 VGSGIGYGAEGEEEDDKTSLLQD----------------EKPQP----------------RFWTF 76

  Fly   111 EYYQQFFNVDTYMVLERIANSMIPKRASGNYLRMNIGENPDLYGPFWITVTLIFSIAISGNIASY 175
            :|||.||:|||..||:||..|::| ....|::|.::...|||||||||..||.|.:|::||:...
  Rat    77 DYYQSFFDVDTSQVLDRIKGSLLP-HPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLV 140

  Fly   176 LQQATDAYKWHYN--FHLVSYAATSIFLYANILPAVLWALFKYSLKPVDSADAVETDSASYMPSL 238
            |.|..|. ..||:  ||.|:.|..:|:.||.::|..||...::         ...|.....:.:.
  Rat   141 LAQRRDP-SIHYSPQFHKVTIAGITIYCYAWLVPLALWGFLRW---------RQGTRERMGLYTF 195

  Fly   239 LSLMCIYGYSLAIYIPVSILWVINISLLQWLLVITAALLSGTVLIAVLTPALRNS----QFSLFL 299
            |..:|:|||||.::||..:||:|.:..||||....|..||...|:..|.|.:|..    ..:|..
  Rat   196 LETVCVYGYSLFVFIPTVVLWLIPVQWLQWLFGALALALSAAGLVFTLWPVVREDTRLVAAALLS 260

  Fly   300 IVGILSAHVVLAAGFLLYFFHNPTVPSLDPVAPTP-AAPAAPAAL 343
            ||.:|  |.:||.|..||||.  .:| ||.|.|.| |.|.:|..|
  Rat   261 IVVLL--HALLALGCKLYFFQ--PLP-LDHVVPAPQAIPPSPNVL 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4645	NP_001285171.1	Yip1	149..310	CDD:282716	59/166 (36%)
Yipf2	NP_001014230.1	Yip1	83..>218	CDD:282716	54/145 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352443
Domainoid	1	1.000	139	1.000	Domainoid score	I4661
eggNOG	1	0.900	-	-		E1_KOG3114
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	177	1.000	Inparanoid score	I3931
OMA	1	1.010	-	-		QHG54497
OrthoDB	1	1.010	-	-		D1425332at2759
OrthoFinder	1	1.000	-	-		FOG0001880
OrthoInspector	1	1.000	-	-		otm46158
orthoMCL	1	0.900	-	-		OOG6_101326
Panther	1	1.100	-	-	LDO	PTHR12822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1411
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770