DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4645 and Yipf1

DIOPT Version :9

Sequence 1:	NP_001285171.1	Gene:	CG4645 / 32244	FlyBaseID:	FBgn0030435	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_006238566.1	Gene:	Yipf1 / 298312	RGDID:	735206	Length:	355	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	115/339 - (33%)
Similarity:	163/339 - (48%)	Gaps:	76/339 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ADDLLQFRDYSGGA--------PAQINVNSPT----HGGSGGSGGGSAGSGGSVGGGGANAQRQR 58
            |.|.|||.::..||        ...||:..|:    |         .....||:|       |:.
  Rat     3 AVDDLQFEEFGDGATLLAANPDATTINIEDPSVSFKH---------QPRPPGSLG-------REE 51

  Fly    59 GDPLADLIYDMTSSAQGFSGAASSGGSQPQNSSLDGSAGGGGGGAKLSLFTIEYYQQFFNVDTYM 123
            .:.|..     |:.:......|....|.|                   .:|.||||.||:||||.
  Rat    52 DEELLG-----TNDSDETELLAGQKKSSP-------------------FWTFEYYQTFFDVDTYQ 92

  Fly   124 VLERIANSMIPKRASGNYLRMNIGENPDLYGPFWITVTLIFSIAISGNIASYLQQATDAYKWHY- 187
            |.:||..|::|.... |::|:.|..||||||||||..||:|:||||||::::|....:. .:||
  Rat    93 VFDRIKGSLLPVPGK-NFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEK-TYHYV 155

  Fly   188 -NFHLVSYAATSIFLYANILPAVLWALFKYSLKPVDSADAVETDSASYMPSLLSLMCIYGYSLAI 251
             .|..||.|||.|:.||.::|..||....:....|       .:..||  |.|.::|:|||||.|
  Rat   156 PEFQKVSIAATVIYAYAWLVPLALWGFLLWRNSKV-------MNIVSY--SFLEIVCVYGYSLFI 211

  Fly   252 YIPVSILWVINISLLQWLLVITAALLSGTVLIAVLTPALR--NSQFSLFLIVGILSAHVVLAAGF 314
            |||.::||:|...:::|:||..|..:||:||.....||:|  |.:.:|..||.|:..||:|:.|.
  Rat   212 YIPTAVLWIIPQRVIRWVLVTIALGISGSVLAMTFWPAVREDNRRVALATIVTIMLLHVLLSVGC 276

  Fly   315 L---------LYFF 319
            |         ||.|
  Rat   277 LVCSYGTHLVLYLF 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4645	NP_001285171.1	Yip1	149..310	CDD:282716	70/164 (43%)
Yipf1	XP_006238566.1	Yip1	100..277	CDD:398520	77/187 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352442
Domainoid	1	1.000	139	1.000	Domainoid score	I4661
eggNOG	1	0.900	-	-		E1_KOG3114
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5898
Inparanoid	1	1.050	177	1.000	Inparanoid score	I3931
OMA	1	1.010	-	-		QHG54497
OrthoDB	1	1.010	-	-		D1425332at2759
OrthoFinder	1	1.000	-	-		FOG0001880
OrthoInspector	1	1.000	-	-		otm46158
orthoMCL	1	0.900	-	-		OOG6_101326
Panther	1	1.100	-	-	O	PTHR12822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1411
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770