DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brms1 and Brms1

DIOPT Version :9

Sequence 1:	NP_572840.1	Gene:	Brms1 / 32243	FlyBaseID:	FBgn0030434	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001009605.1	Gene:	Brms1 / 293668	RGDID:	1311057	Length:	246	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	95/240 - (39%)
Similarity:	145/240 - (60%)	Gaps:	24/240 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPV-----KNGESDGEGDVS---GGESEHSNSSQPHDTSDEEEANECDSDDSSELDASEIDRRRA 57
            ||:     :..|.:.|||.:   .||::.|...:....::.||       :|||:|..:.:|||:
  Rat     1 MPIQPSGKETEEMEAEGDSAAEMNGEADESEEERSGSQTESEE-------ESSEMDDEDYERRRS 58

  Fly    58 EHIEDLLSLERQFNELREQYYVERINLIERQLAEVRSGRSEEFVQPQKELDKKYRTRIEVADVLR 122
            |.:.::|.||:||:||:|:.:.||::.:..:|.||.:.|:.|:.:|...|.:..:.||:||.:.:
  Rat    59 ECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQQSLKIRIQVAGIYK 123

  Fly   123 KYRLQNIEHKYQSEEQAAVQHFESEKHMALDNLREEFMERIRRLEEDRHNVDISWADWGTDKRQS 187
            .:.|..|.:||:.|.|.|.||.||||.:..|.|..|..|||:||||||.::||| ::|..||..|
  Rat   124 GFCLDVIRNKYECELQGAKQHLESEKLLLYDTLLGELQERIQRLEEDRQSLDIS-SEWWDDKLHS 187

  Fly   188 K--------VRGPGRKKAVTVTGPYVVYMLREEDIMEDWTIIRKA 224
            :        |....||||..|:|||:||||:|.||:||||.|:||
  Rat   188 RGSSKTWDSVPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKA 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brms1	NP_572840.1	Sds3	59..>176	CDD:285764	47/116 (41%)
Brms1	NP_001009605.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..57		17/63 (27%)
Brms1	NP_001009605.1	Sds3	60..>177	CDD:400770	48/116 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337296
Domainoid	1	1.000	104	1.000	Domainoid score	I6554
eggNOG	1	0.900	-	-		E1_KOG4466
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I3958
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1456563at2759
OrthoFinder	1	1.000	-	-		FOG0002914
OrthoInspector	1	1.000	-	-		otm44471
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21964
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1923
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.860