DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brms1 and brms1l

DIOPT Version :9

Sequence 1:	NP_572840.1	Gene:	Brms1 / 32243	FlyBaseID:	FBgn0030434	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001096366.1	Gene:	brms1l / 100124958	XenbaseID:	XB-GENE-1002972	Length:	322	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	90/232 - (38%)
Similarity:	145/232 - (62%)	Gaps:	9/232 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPVKNGE--SDGEGDVSGGESEHSNSSQPHDTSDEEEANECDSDDSSELDASEIDRRRAEHIEDL 63
            |||.:.|  .....|:.....|:..:|...|.||....:|  ..||||:|..:.:|||.|.::::
Frog     1 MPVHSREKKESNHNDMEVDYPENEGTSSEEDDSDSSSGSE--EGDSSEMDDEDCERRRMECLDEM 63

  Fly    64 LSLERQFNELREQYYVERINLIERQLAEVRSGRSEEFVQPQKELDKKYRTRIEVADVLRKYRLQN 128
            .:||:||.:|::|.|.||::.::.:|.||.:|::.|:::|...|.:..:.|.:||.:.|:..|::
Frog    64 SNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLANLQENMQIRTKVAGIYRELCLES 128

  Fly   129 IEHKYQSEEQAAVQHFESEKHMALDNLREEFMERIRRLEEDRHNVDISWADWGTD-----KRQSK 188
            :::|:..|.|||.||.||||.:..|.::.|..|:|||||||||::||:...|..:     ||:..
Frog   129 VKNKHDCEIQAARQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRRKRKDP 193

  Fly   189 VRGPGRKKAVTVTGPYVVYMLREEDIMEDWTIIRKAL 225
            .....:||.|.|:|||:||||::.||:||||.||||:
Frog   194 FSPDKKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAM 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brms1	NP_572840.1	Sds3	59..>176	CDD:285764	45/116 (39%)
brms1l	NP_001096366.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..56		17/56 (30%)
brms1l	NP_001096366.1	Sds3	59..>177	CDD:369987	46/117 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5957
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9123
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3914
OMA	1	1.010	-	-		QHG49521
OrthoDB	1	1.010	-	-		D1456563at2759
OrthoFinder	1	1.000	-	-		FOG0002914
OrthoInspector	1	1.000	-	-		otm47517
Panther	1	1.100	-	-	O	PTHR21964
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5740
SonicParanoid	1	1.000	-	-		X1923
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110