DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Brms1 and brms1

DIOPT Version :9

Sequence 1:	NP_572840.1	Gene:	Brms1 / 32243	FlyBaseID:	FBgn0030434	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	XP_002939374.2	Gene:	brms1 / 100036672	XenbaseID:	XB-GENE-992989	Length:	316	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	97/243 - (39%)
Similarity:	154/243 - (63%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ESDGEGDVSGGESEHSNSSQPHDTSDEEEANECDS-DDSSELDASEIDRRRAEHIEDLLSLERQF 70
            |:|...:::|.|..        ||..|:.|::.|| ::||::|..:.:|||.|.::::..||:||
Frog     5 EADSAAEMNGQEEA--------DTDGEDSASQSDSEEESSDMDDLDCERRRNECLDEMCHLEKQF 61

  Fly    71 NELREQYYVERINLIERQLAEVRSGRSEEFVQPQKELDKKYRTRIEVADVLRKYRLQNIEHKYQS 135
            :||:|:.:.||:|.::.:|.||.|||:.|::.|..||.|..:.|||||.:.:.:.|..|:|:|:.
Frog    62 SELKEKLFKERLNELKAKLEEVNSGRAMEYINPLAELQKNMKIRIEVAGIYKGFCLDVIKHRYEC 126

  Fly   136 EEQAAVQHFESEKHMALDNLREEFMERIRRLEEDRHNVDISWADWGTDKRQSK--------VRGP 192
            |.|.|.||.||||.:..||::.|.:|||:||||||.::||| ::|..::.:||        .|..
Frog   127 EVQGAKQHLESEKVLLFDNMQCELLERIQRLEEDRQSIDIS-SEWWDEELRSKRNRKKWDPFRSE 190

  Fly   193 GRKKAVTVTGPYVVYMLREEDIMEDWTIIRKA------LKRSSSSATA 234
            .:::...|:|||:|||||:.||:||||.|:||      .||.|.:..|
Frog   191 KKRRVPLVSGPYIVYMLRDLDILEDWTAIKKAKAAVSPQKRKSDNVKA 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Brms1	NP_572840.1	Sds3	59..>176	CDD:285764	52/116 (45%)
brms1	XP_002939374.2	Sds3	50..>178	CDD:369987	55/128 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5957
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3914
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1456563at2759
OrthoFinder	1	1.000	-	-		FOG0002914
OrthoInspector	1	1.000	-	-		otm47517
Panther	1	1.100	-	-	LDO	PTHR21964
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1923
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160