DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4404 and hng2

DIOPT Version :9

Sequence 1:NP_572838.2 Gene:CG4404 / 32241 FlyBaseID:FBgn0030432 Length:308 Species:Drosophila melanogaster
Sequence 2:NP_649837.1 Gene:hng2 / 41056 FlyBaseID:FBgn0037634 Length:254 Species:Drosophila melanogaster


Alignment Length:305 Identity:59/305 - (19%)
Similarity:111/305 - (36%) Gaps:88/305 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 FVQFVENQPCLWNYTHPGYSKKEDVQRAWQQVANDI------------KDTVRNCRERWRTIRSS 70
            |:..|..:..:|..:||.:..:|....||||:.:::            ::.|:...:||:..|.|
  Fly    21 FIDAVHKRSIIWERSHPNFHNRELRDEAWQQIGHELCSNFDDSSEPEKQEIVKTLLKRWKNTRDS 85

  Fly    71 FLRSLKLARTQTGRGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMVLRKPGQAATAQQEDEVVAAE 135
            :||..:|.::.....:..|...|.|.||:                      ...|:.||:|.:.:
  Fly    86 YLRVNRLRQSGEEVARASYIYEKELSFLL----------------------NVKAESEDDVESLK 128

  Fly   136 EEAKVSDGEMPLDVQVSEEEHRRNQEQDREQPTACLPLRLHSIKVEHDSSNANQQLERMVSQQSL 200
            |:.|              .:.:|.:.....|.:|..|.:        .:|:....:|..:...::
  Fly   129 EQPK--------------PQAKRKRVSTAAQRSAKTPRK--------RNSDQESNIEPAIRNPAI 171

  Fly   201 VSVPAAALGNHLGWSDLTQWFKGHGSGHHKLTTTTT----TPTSPPPPP-QPATSALSVFTGGPG 260
            .|.....||      ||         |..|..|.|.    .|..|..|| ...|:.||.      
  Fly   172 PSNINTVLG------DL---------GCAKEDTATPEIAYIPQLPSDPPCSTNTAYLSA------ 215

  Fly   261 GGGSQPDADYSFLISLHPYIKEMNGKQNRKFRQKVVGLIDDILDN 305
                  |.|.:|..::.|::::|...:...|:.:|:.::.:...|
  Fly   216 ------DPDQAFFDTIKPHMQQMCADRKLDFQIEVLKILRNFKPN 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4404NP_572838.2 MADF 17..103 CDD:214738 23/96 (24%)
BESS 267..301 CDD:281011 7/33 (21%)
hng2NP_649837.1 MADF_DNA_bdg 21..113 CDD:287510 21/91 (23%)
BESS 216..250 CDD:281011 7/33 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45469749
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001895
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.840

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