DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4404 and CG9948

DIOPT Version :9

Sequence 1:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001261492.1	Gene:	CG9948 / 38757	FlyBaseID:	FBgn0035721	Length:	218	Species:	Drosophila melanogaster

Alignment Length:	225	Identity:	51/225 - (22%)
Similarity:	86/225 - (38%)	Gaps:	42/225 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RKDDPVFNVRFVQFVENQPCLWNYTHPGYSK------KEDVQRAWQQVANDIKDTVRNCRERWRT 66
            :|:.| |:.:.:..||..|.|  |...|.|.      |.|:   |.::|..:...|..|..||..
  Fly     6 KKNRP-FDFKLIDLVEPNPVL--YKRSGLSNYDAMKAKTDI---WARIAEMMGCDVDFCLMRWNN 64

  Fly    67 IRSSFLRSLKLARTQTGRGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMVLRKP---GQAATAQQE 128
            :...|.:..:.|.|.   |....||.: |:||...        |.|..|..||   .|.||.|.|
  Fly    65 LHYQFRKEFRRADTS---GSTWPYLER-LRFLAEI--------QPPSKVKTKPKTNKQEATIQTE 117

  Fly   129 DEVVAAEEEAKVSDGEMP-------LDVQVSEEEHRRNQEQ---DREQPTACLPLRLHSIKVEHD 183
            ..|....:  ...||::|       ::..:.|...:..||:   :.::|...:..|...::::..
  Fly   118 TPVQFLWD--TFEDGDVPQQSSTFIIEEVIEEPSEQIIQEEIIYEEQEPAEIISPRSSFLQMDQI 180

  Fly   184 SSNANQQLERMVSQQ---SLVSVPAAALGN 210
            .:...:...|...::   .|:.....||.|
  Fly   181 LAQLKEPQRRRAERRITAFLLKCQLRALSN 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4404	NP_572838.2	MADF	17..103	CDD:214738	24/91 (26%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
CG9948	NP_001261492.1	MADF	14..95	CDD:214738	24/89 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100