DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4404 and CG10949

DIOPT Version :9

Sequence 1:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	57/248 - (22%)
Similarity:	103/248 - (41%)	Gaps:	46/248 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RKD-------DPVFNVRFVQFVENQPCLWNYTHPGYSKKEDVQ-RAWQQVANDIKDTVRNCRERW 64
            |||       |.:.|.:.::.|::.|.|::......||....: .||::::.::..:...|..||
  Fly   124 RKDEEEEDSQDDLLNEQLIELVKSHPVLYDRHKIRVSKNLAAKNEAWREISENLNVSEELCYNRW 188

  Fly    65 RTIRSSFLRSLKLAR-TQTGRGKRKY-----YLSKYLQFLVPF---------------TKSRSCH 108
            :.:|..|.|..:..: .|:.....:|     :|.::.:..||.               ..|....
  Fly   189 KKLRDRFGREFRSHQINQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAGNPSGKTS 253

  Fly   109 KQLPGMVLRKPGQAATAQ----------QEDEVVAAEEEAKV-SDGEM--PLDVQVSEEEHRRNQ 160
            ||..|||:....|...|.          ::|..:|.:||.:: |:.|.  |.|..:||...|::.
  Fly   254 KQPEGMVISSGEQIWGADYPYSTDNDDLEDDLELAYDEEIEILSEAEQATPYDFILSEATARQDL 318

  Fly   161 EQDRE-QPTACLPLRLHSIKVEHDSSNANQQLERMVSQQSLVSVPAAALGNHL 212
            |..:: |.|...|..  |.::.|..:..|..:|...|... .|||:||:.:.|
  Fly   319 EPPQQLQVTTTTPAT--SEEIIHTIARVNPVVEESSSLPG-DSVPSAAISDKL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4404	NP_572838.2	MADF	17..103	CDD:214738	18/107 (17%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	16/85 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940