DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4404 and madf-10

DIOPT Version :9

Sequence 1:	NP_572838.2	Gene:	CG4404 / 32241	FlyBaseID:	FBgn0030432	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_492729.1	Gene:	madf-10 / 190925	WormBaseID:	WBGene00013717	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	48/217 - (22%)
Similarity:	84/217 - (38%)	Gaps:	58/217 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 NVRFV--QFVENQPCLWNYTHPGYSK-------KEDVQRAWQQVANDIKDTVRNCRERWRTIRSS 70
            :|||.  :.:.::|.||:.|....|.       .|.|:...||.......|:....:.|:.::.:
Worm    48 SVRFAMCEAIAHRPGLWDSTREKVSSAARKNLFAEVVEVINQQFVLSPPLTIEEIEKHWKNLKDT 112

  Fly    71 FLRS-LKLARTQTG---RGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMVLRKPGQAATAQQEDEV 131
            :::: .||.....|   |.|.|::.|  |.||....::....|:.|   ::..||.....|.
Worm   113 YVKTRRKLTFDHDGCPIRPKWKFFDS--LMFLDSVNQNDFVMKKRP---MQFQGQPYDLYQG--- 169

  Fly   132 VAAEEEAKVSDGEMPLDVQVSEEEHRRNQEQDREQPTAC----LPL-------RLHSIKVEHDSS 185
             .:.::.|:.  |||.|                |....|    |||       |:|.:|::
Worm   170 -PSSKKEKLE--EMPSD----------------EYMEFCRSLYLPLKEIGYKDRIHWLKIQ---- 211

  Fly   186 NANQQLERMVSQQSLVSVPAAA 207
               :.:..:|.:..|.||..||
Worm   212 ---KSIRDIVYEAQLESVTKAA 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4404	NP_572838.2	MADF	17..103	CDD:214738	23/98 (23%)
CG4404	NP_572838.2	BESS	267..301	CDD:281011
madf-10	NP_492729.1	MADF	53..147	CDD:214738	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001895
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930