DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXC8 and Ubx

DIOPT Version :9

Sequence 1:NP_073149.1 Gene:HOXC8 / 3224 HGNCID:5129 Length:242 Species:Homo sapiens
Sequence 2:NP_536752.1 Gene:Ubx / 42034 FlyBaseID:FBgn0003944 Length:389 Species:Drosophila melanogaster


Alignment Length:221 Identity:79/221 - (35%)
Similarity:109/221 - (49%) Gaps:60/221 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    39 VYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNP-CSLSCHGDASK--------------F 88
            |.|..|:|.|.|..            .|::.:|...|. |::|  |.|::              |
  Fly   189 VSGGNGNAGGVQSG------------VGVAGAGTAWNANCTIS--GAAAQTAAASSLHQASNHTF 239

Human    89 YGYEAL-------PRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHA 146
            |.:.|:       |.:|    :..:.:.||....:......||       :.:.||:..|:..:.
  Fly   240 YPWMAIAGECPEDPTKS----KIRSDLTQYGGISTDMGKRYSE-------SLAGSLLPDWLGTNG 293

Human   147 PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKD 211
            . ||.|||||:|||||||||||..|.||||:||||::|||.|||||:||||||||||.|||....
  Fly   294 L-RRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAI 357

Human   212 KLPGARDEEKVEEEGNEEEEKEEEEK 237
            |            |.||:|::.:.:|
  Fly   358 K------------ELNEQEKQAQAQK 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXC8NP_073149.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..154 8/39 (21%)
Antp-type hexapeptide 138..143 1/4 (25%)
Homeobox 153..205 CDD:306543 42/51 (82%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 206..242 8/32 (25%)
UbxNP_536752.1 Homeobox 299..352 CDD:395001 42/52 (81%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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