Protein Alignment HOXC8 and Scr

DIOPT Version :10

• Sequence 1: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 79/214 - (36%)
• Similarity: 102/214 - (47%)
• Gaps: 53/214 - (24%)

Human    42 PGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQ---NPCSLSCHGDASKFYG---YEALPRQ--- 97
            ||||..|....|:      ::..|..||:...|   :|..||....:.|...   .|::.|.
  Fly   176 PGGSGGGGVSGSN------NNNNSANSNNNNSQSLASPQDLSTRDISPKLSPSSVVESVARSLNK 234

Human    98 -----SLYGAQQEASV---------------VQYP---------DCKSSANTNSSEGQGHLNQNS 133
                 ||..|...|.:               |..|         |.:|.:...:...|...|...
  Fly   235 GVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGNGKK 299

Human   134 SPSLMFPWM-RPH-------APGR-RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLT 189
            :|..::||| |.|       |.|. :..|.:|:|||||||||||.||.||||:||||::|||.||
  Fly   300 NPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 364

Human   190 ERQVKIWFQNRRMKWKKEN 208
            |||:||||||||||||||:
  Fly   365 ERQIKIWFQNRRMKWKKEH 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		11/48 (23%)
		Antp-type hexapeptide	138..143		3/5 (60%)
		Homeodomain	150..206	CDD:459649	42/55 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		2/3 (67%)
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	42/55 (76%)