Protein Alignment HOXC8 and vnd

DIOPT Version :10

• Sequence 1: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Sequence 2: NP_476786.2
• Gene: vnd / 31003
• FlyBaseID: FBgn0261930
• Length: 723
• Species: Drosophila melanogaster
• Alignment Length: 169
• Identity: 46/169 - (27%)
• Similarity: 75/169 - (44%)
• Gaps: 22/169 - (13%)

Human    56 VQDFFH--HGTSGISNSGYQQNPCSLSCHGDASKFYGYEALPRQSLYGA-------QQEASVVQY 111
            |.|..|  ||:||..::|......:|..:.:.:......:|..:.:.||       ..|..:.:.
  Fly   456 VGDALHTLHGSSGNGSAGGAPTAHALHNNNNNTTNNNNHSLKAEGINGAGSGHDDSLNEDGIEED 520

Human   112 PDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTR 176
            .|     :.:.::|.|..:.|.|..|      |:.  :|..|..:::.||.|||:.|....||:.
  Fly   521 ID-----DVDDADGSGGGDANGSDGL------PNK--KRKRRVLFTKAQTYELERRFRQQRYLSA 572

Human   177 KRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPG 215
            ..|..::..:.||..||||||||.|.|.|:..|:....|
  Fly   573 PEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNEKGYEG 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		7/39 (18%)
		Antp-type hexapeptide	138..143		0/4 (0%)
		Homeodomain	150..206	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		2/10 (20%)
vnd	NP_476786.2	Homeodomain	546..602	CDD:459649	23/55 (42%)