Protein Alignment HOXC8 and ind

DIOPT Version :10

• Sequence 1: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Sequence 2: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 70/239 - (29%)
• Similarity: 100/239 - (41%)
• Gaps: 59/239 - (24%)

Human    21 PAYYDCRFPQSVG-----------RSHALVYGPGGSAPG----FQHASHHVQDFFH--------- 61
            ||.|...:..|:|           :.||.......:|..    ..|.|......:|
  Fly    52 PASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASK 116

Human    62 HGTSGISN-SGYQQNPCSLSCHGDASKFYGYEALPRQSLYGA--------QQEASVVQYPDCKSS 117
            ..:||.|| .|...:| .||.:.::.     :..|..:|||:        .:..|....|...||
  Fly   117 RKSSGFSNYEGCYPSP-PLSANPNSQ-----QLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSS 175

Human   118 AN----TNSSEGQG-------HLNQNSSPSL---------MFPWMRPHAPGRRSGRQTYSRYQTL 162
            |:    .|..|.||       ..:.||||..         :.|.:..:|...:..|..::..|.|
  Fly   176 ASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLL 240

Human   163 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKK 206
            |||:||..|.||:|.||||:::.|.|:|:||||||||||:|.||
  Fly   241 ELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		13/59 (22%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeodomain	150..206	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		1/1 (100%)
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	30/55 (55%)