Protein Alignment Coq8 and ADCK2

DIOPT Version :9

• Sequence 1: NP_572836.1
• Gene: Coq8 / 32239
• FlyBaseID: FBgn0052649
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_443085.2
• Gene: ADCK2 / 90956
• HGNCID: 19039
• Length: 626
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 108/593 - (18%)
• Similarity: 185/593 - (31%)
• Gaps: 225/593 - (37%)

  Fly   223 VAKQRKV---------PSSRIGRMASFGGLFAGLGLGTLNELTKGAL-----------GLGGSTS 267
            |..:|:|         |:..:.|....||:|..|.|.    |..|||           .|
Human    64 VLSRRRVRCSGAAGAGPAESLPRAGPLGGVFLHLRLW----LRAGALLVKFFPLLLLYPL----- 119

  Fly   268 MREALLSPANAERIVDTLCKVRGAA----LKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDW 328
               ..|:|:.:...:..|.|....:    :|:||..|.: ..:.|......|.::.......|..
Human   120 ---TYLAPSVSTLWLHLLLKATETSGPTYIKLGQWASTR-RDLFSEAFCAQFSKLHVRVTPHPWT 180

  Fly   329 QVERVMNTQLGADWRQRLKSFEDK-PFAAASIGQVHRA--------------------------- 365
            ..||.:....|.||...| |||:: |..:..:.||::|
Human   181 HTERFLRQAFGDDWGSIL-SFENREPVGSGCVAQVYKAYANTAFLETDSVQRLGRASCLPPFSHT 244

  Fly   366 ---------------------TLSDG-----------------------------------MDVA 374
                                 .|:|.                                   :.||
Human   245 GAVGGLRELFGYLGNGRKPPENLADQSFLERLLLPKADLVGSNAGVSRAQVPGHQPEATNLISVA 309

  Fly   375 IKIQYPGVAQSIESDI------DNLVGMLK--VWDVFPQGFFIDNVVRVAKRELQWEVDYDREAE 431
            :|:.:||:...:..|:      ..::|:|.  .|...|:      :|...::.:..::|...||:
Human   310 VKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPE------IVEEFEKLMVQQIDLRYEAQ 368

  Fly   432 YTEKFREMIAPYPEYYVPRVVRDLTTSSVLT---TELVP-------GVPLDKCFDLSYEHRRHIA 486
            ..|.|:...........|..:|...|..||.   .|.||       |:|:|.        :|.||
Human   369 NLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVPVSSYQQAGIPVDL--------KRKIA 425

  Fly   487 ASVLKLCLRELFEIECMQTDPNWSNFLYD-------------------------APSR----RLM 522
            ...:.:.|:.:|....:..|.:..|.|..                         .||.    ||:
Human   426 RLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVAVPSSLCPLRLV 490

  Fly   523 LIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEM------SREMGFLTGYETKQ--------- 572
            |:|.|.....:...:||:|.|.|:......|.|.|:      :.|...:.|::|:.
Human   491 LLDAGIVAELQAPDLRNFRAVFMAVVMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARK 555

  Fly   573 ----MEQAHVDAVMILGEIF--------RYDGDF-----------DFGR--QNTTERLAALVPTM 612
                :|:.||.:  :|..:|        :.:.:|           ..||  ....:.|.|..|.:
Human   556 NTITLEKLHVSS--LLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAARPFL 618

  Fly   613 VAHRLCPP 620
            :...:|||
Human   619 LTGPVCPP 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coq8	NP_572836.1	AarF	262..641	CDD:223733	94/534 (18%)
		ABC1_ADCK3	313..563	CDD:270872	68/386 (18%)
ADCK2	NP_443085.2	AarF	134..618	CDD:223733	88/501 (18%)
		ADCK2-like	169..553	CDD:270873	69/398 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810