Protein Alignment Coq8 and Coq8a

DIOPT Version :9

• Sequence 1: NP_572836.1
• Gene: Coq8 / 32239
• FlyBaseID: FBgn0052649
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001013203.1
• Gene: Coq8a / 360887
• RGDID: 1308245
• Length: 649
• Species: Rattus norvegicus
• Alignment Length: 637
• Identity: 273/637 - (42%)
• Similarity: 376/637 - (59%)
• Gaps: 63/637 - (9%)

  Fly    65 LKKLQQTVKET-------GERGYVVAKGICSLLETKIKM---------SREESAISEPAQ--VSS 111
            |.||.|...||       |....:.|:.:.|....:|.|         ..|:|..:|..:  .:.
  Rat    15 LAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDSYATENFEDLEAE 79

  Fly   112 IRKSTPTA--QNPASWDAANLDISSITLQEFEEILSRRNKD-------RSVSLRTPATKSNQTMP 167
            ::.|||.|  .:|....|::||      |.....|...:::       .|...|........|.|
  Rat    80 VQFSTPQAAGSSPDFSTASSLD------QPLSSSLGHAHREGPAPAYVSSGPFREAGLSGQATSP 138

  Fly   168 KKETSTNPGIITQDTEYVNNVLRF--------VAGAKVEE--------QPPDAQPKKKSDQPAIE 216
            ....:....:..:|....|::.|.        |.|...|:        ..|:::|.|:.
  Rat   139 LGRVNGRLFVDCRDLFLANSIQRRFFHQDQAPVGGLTAEDIEKARQAKARPESKPHKQM------ 197

  Fly   217 VPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREAL-----LSPA 276
               ||:.|::||||.:||||:|:||||..|||.|.|.|:.|.:|....||..:..|     ||.|
  Rat   198 ---LSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSENSTGKKAVLDSSPFLSEA 259

  Fly   277 NAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGAD 341
            ||||||.|||||||||||:||:|||||.:.::|.|||.||||||:||:||..|:.:.:|..||..
  Rat   260 NAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPH 324

  Fly   342 WRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQG 406
            ||.:|:.||::|||||||||||.|.|..|.:||:|||||||||||.||::||:.:|.:.::.|:|
  Rat   325 WRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEG 389

  Fly   407 FFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPL 471
            .|.::::.|.:|||..|.||.|||.|.:||||::..:|.:|||.:|.:|.:..||||||:.|.||
  Rat   390 LFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPL 454

  Fly   472 DKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEF 536
            |:...||.|.|..|..::|.||||||||...||||||||||.||....::.|:|||:||.|...|
  Rat   455 DQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSF 519

  Fly   537 IRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNT 601
            ...|.:||.:||:.:|:.||:.|.||.||||||.|.||.||:||::||||.|..:..||||.|:|
  Rat   520 TDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQST 584

  Fly   602 TERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKD 653
            ||::..|:|.|:.|||.|||||.||:|||:.|.||:|::|.....|...:::
  Rat   585 TEKIHNLIPIMLKHRLIPPPEETYSLHRKMGGSFLICSKLKACFPCKAMFEE 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coq8	NP_572836.1	AarF	262..641	CDD:223733	210/383 (55%)
		ABC1_ADCK3	313..563	CDD:270872	130/249 (52%)
Coq8a	NP_001013203.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..125		10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..203		5/28 (18%)
		KxGQ motif. /evidence=ECO:0000250|UniProtKB:Q8NI60	277..280		1/2 (50%)
		ABC1_ADCK3	296..546	CDD:270872	130/249 (52%)
		AAAS motif. /evidence=ECO:0000250|UniProtKB:Q8NI60	338..341		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2598
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1443
OMA	1	1.010	-	-		QHG53666
OrthoDB	1	1.010	-	-		D128317at33208
OrthoFinder	1	1.000	-	-		FOG0001764
OrthoInspector	1	1.000	-	-		otm44424
orthoMCL	1	0.900	-	-		OOG6_101512
Panther	1	1.100	-	-	O	PTHR43851
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1120
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840