DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Coq8 and SPBC15C4.02

DIOPT Version :9

Sequence 1:	NP_572836.1	Gene:	Coq8 / 32239	FlyBaseID:	FBgn0052649	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_595922.2	Gene:	SPBC15C4.02 / 2539608	PomBaseID:	SPBC15C4.02	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	522	Identity:	113/522 - (21%)
Similarity:	198/522 - (37%)	Gaps:	103/522 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 PKKKSD---------------QPAI---EVPELSKVA-------KQRKVPSSRIGRMASFGGL-F 244
            |||||.               :||:   .:..::.||       |...|.|.|..|:...|.| |
pombe    18 PKKKSSCISFTHHAREHTNFKKPAVVGASITLMASVALVDFDPVKHAGVSSKRAYRVVLAGFLCF 82

  Fly   245 AGLGLGTLNELTKGALGLG-GSTSMREALLSPAN---AERIVDTLCKVRGAALKIGQILSIQDSS 305
            :..         |..||.. .|...|:..||..:   |||.:....:..|..:||||.||.. ..
pombe    83 SDY---------KKVLGSSYASEEERQLALSECHLRCAERSLKVFEENGGIYIKIGQHLSAM-GY 137

  Fly   306 VVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDG 370
            |:..:......:::..........::.:.....|....:....|:......||:.|||:|.|.|.
pombe   138 VIPKEWTNTMVKLQDRCPSTSLKDIDHLFRVDTGKGLDETFDEFDPIALGVASLAQVHKARLKDS 202

  Fly   371 -MDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTE 434
             :.||:|:|:|.|:.:...|:.....:.|....|...|.:..:....:|.|..|:|:.|||:.:.
pombe   203 DVWVAVKVQHPSVSLNSPLDLSMTRWVFKAIKTFFPDFKLMWLADEIERSLPQELDFTREAKNSI 267

  Fly   435 KFREMIAPY-PEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELF 498
            :.:|..|.. ...|||.|:  .:...:|..|.|.|..:|   :||:.....|:..::.:.:..:|
pombe   268 ETKEHFAHLSTSLYVPEVM--WSKPRILVMEYVAGARID---NLSFMDEHSISRDLVSVDICHIF 327

  Fly   499 ---------EIECMQTDPNWSNFLYDAPSR--------RLMLIDFGSTRFYRHEFIRNYRRVIMS 546
                     .:.|   ||:..|.|..:..:        .::|:|.|..|...||...:|..:.::
pombe   328 NEMIFGKGGHLHC---DPHGGNVLIRSKPKNSKSPRNYEIVLLDHGLYRDIPHELQVDYANMWLN 389

  Fly   547 AAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNTTE-------- 603
            ....|.:.:...::::..::.      |...:.|..|.|..::.......|..|..|
pombe   390 IINFNEKNLKFYAKKVANVSD------ENFPIFATAITGRPYKSLKSLPIGGPNHEEEQKKFISA 448

  Fly   604 -----------RLAALVPTMVAHRLCPPPEEIYSIHRKL---SG---IFLLCARLNVRMNCVPFY 651
                       ||.:.:|.:.. .|....:.:.|:...|   ||   ::|:.||..:|  ||  |
pombe   449 LQKGGMLQSIIRLLSTMPRLTL-LLMKTNDLVRSLDENLKTKSGPEKLYLIMARYCLR--CV--Y 508

  Fly   652 KD 653
            .|
pombe   509 DD 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq8	NP_572836.1	AarF	262..641	CDD:223733	87/426 (20%)
Coq8	NP_572836.1	ABC1_ADCK3	313..563	CDD:270872	55/268 (21%)
SPBC15C4.02	NP_595922.2	AarF	50..557	CDD:223733	106/490 (22%)
SPBC15C4.02	NP_595922.2	ADCK1-like	149..404	CDD:270871	55/262 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810