Protein Alignment Coq8 and ADCK5

DIOPT Version :9

• Sequence 1: NP_572836.1
• Gene: Coq8 / 32239
• FlyBaseID: FBgn0052649
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: XP_011515209.1
• Gene: ADCK5 / 203054
• HGNCID: 21738
• Length: 654
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 126/542 - (23%)
• Similarity: 193/542 - (35%)
• Gaps: 174/542 - (32%)

  Fly   186 NNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLG 250
            |.|||     .|||..|.             ..|:.....||...:...|.::: |||:..||.|
Human   180 NVVLR-----GVEENSPG-------------YLEVMSACHQRAADALVAGAISN-GGLYVKLGQG 225

  Fly   251 --TLNELTKGALGLGGSTSMREALLSPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAK 313
              :.|.                 ||.|    ....||..:...|||.|
Human   226 LCSFNH-----------------LLPP----EYTRTLRVLEDRALKRG----------------- 252

  Fly   314 AFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQ 378
             |:.|.:.  ::.|:|          |...:..:.|:.:|.||||:.|||||.|.||..||:|:|
Human   253 -FQEVDEL--FLEDFQ----------ALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQ 304

  Fly   379 YPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPY 443
            |..:....:.||..|..:|::.:|....|....|::..|..|..|:|::.|....|:....:|.:
Human   305 YIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHF 369

  Fly   444 PEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYE----HRRHIAASVLKLCLRELFEIECMQ 504
            |...||||..|.::..|||.:...|..::....:..:    |  .||..::|....::|....:.
Human   370 PYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVH--DIAEKLIKAFAEQIFYTGFIH 432

  Fly   505 TDPNWSNFLY-DAPSRR--LMLIDFGSTRFY----RHEFIRNYRRVIM--------SAAENNRQG 554
            :||:..|.|. ..|..:  |:|:|.|..:|.    |....:.:|.:|:        .||....|.
Human   433 SDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQD 497

  Fly   555 VL---EMSRE----MGFLTGYETKQMEQA---------HVDAVM-ILGEIFR------------- 589
            .|   ||..:    :|.|.|......|:|         ..:||| :|.|:.|
Human   498 YLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVR 562

  Fly   590 -------------------------------YDG-----------------DFDFGRQNTT--ER 604
                                           |.|                 .|:...:..|  .|
Human   563 AINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMR 627

  Fly   605 LAALVPTMVAH-RLCPPPEEIY 625
            |.||:...:.| .|.||.||:|
Human   628 LTALLARALVHLSLVPPAEELY 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Coq8	NP_572836.1	AarF	262..641	CDD:223733	107/464 (23%)
		ABC1_ADCK3	313..563	CDD:270872	72/275 (26%)
ADCK5	XP_011515209.1	AarF	202..>482	CDD:223733	85/333 (26%)
		ADCK1-like	243..483	CDD:270871	70/271 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810