Protein Alignment Nep6 and Nepl15

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 164/735 - (22%)
• Similarity: 271/735 - (36%)
• Gaps: 182/735 - (24%)

  Fly    19 LLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIRY 83
            :|:||.|...:..:.   |.:.:.|.||:.|||.||     .|:..|.  :||...|       |
  Fly    36 ILRLAKAAHIKAYMG---DEKEQACNNFYNYACANW-----PRLHPAR--KSKTRTN-------Y 83

  Fly    84 LEE------SSSTDSFSANTSVTTSTA--QLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANH 140
            |||      ..|.|...:.|....::|  ||...|..|.|.....|:..:.|..       :.:.
  Fly    84 LEELQELYIRKSADMLKSATRGAENSADRQLKYFYGSCRLQTNDTRSALNTLQN-------VTDF 141

  Fly   141 TGG------------SFDW--VLAN-------------AALRTYGAQGLWRLLVKDNWQSADQRI 178
            .||            .:||  |:||             ..:..|..:.:.||.:........:|
  Fly   142 RGGWPEIRVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRR- 205

  Fly   179 FYMLPPKFDLLGRDDELNEFLYQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQT 243
             :.|.|.|:   ...|:.|...:..||:...|.....|:.  :|.::|..|:.|.|.||::...|
  Fly   206 -HYLHPHFE---GTREIYERSIENKLKLYFPEQSEHWRQE--VASQVVQIEQQLAKGLPHNPALT 264

  Fly   244 LV-LRKPQSLKDLESQL-PRLELKRYFETILEGIDWDSKTLLLVADL-----DYLQGLQRLLAEH 301
            |. ..:.::..::::.. ..:::.||.:.|..    |:    |..||     ||:..|..::.|.
  Fly   265 LAQTTRQRTAAEMKTAYGSYVDVTRYLQLIFN----DN----LYMDLYETPEDYMSNLVDVIRET 321

  Fly   302 TSDPMVLST-WLLLQ------LPAYFELRLHDDDKLGNQRNH--CLEQLRKLMPGQLGRL----- 352
            ....:...| |..|:      :||             :||..  |::..::..|.||..|
  Fly   322 PKLQLANYTMWKALEALDIARVPA-------------SQRADIWCVQLAQQFFPHQLESLFHRNY 373

  Fly   353 -QMQLV--LGESYQDVYDTAIQQIAVLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLL 414
             .||::  |..::.|        |..:||:..|..|.:|..|      |.||..|..||.|::|.
  Fly   374 NHMQMINELQSTWSD--------IKRVFREDLQASERLLWLT------LETRQKAITKLEALKLH 424

  Fly   415 TPRLQDPINGGPGTPQLGG---NCD---ANLLQLSLSQAKLEYRQVFGEPVTSVPADPLSVNAYY 473
            .....|    .....|:.|   |.|   .||:.:...:.:....::..|||..   |.:....:|
  Fly   425 FRTHDD----NKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAE---DEVHKLPHY 482

  Fly   474 RLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANG 538
            .::.|||::|:..:.......    .|.......|.||.:||.:|:|.||..|..|||.| ..|.
  Fly   483 EIQKNRIQVPITFLQARFFWD----PAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYG-YKNN 542

  Fly   539 QWSARAIIRFGLRAGCY-----LGVRY----------------SNATLTVN--------ENIADT 574
            .|...:...:..|..|:     :.|.|                .|..|.:.        :|.|:|
  Fly   543 WWDHTSESSYSRRTQCFQEQYAIFVEYKGKPVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAET 607

  Fly   575 EGL----RLALDTYRHRSGATNLRTFFVAFAQNWCGTVASTSGLSQHAGHAERVNNVVGNMPEFG 635
            ..:    ||.|..:.|.      :.|::.:||.:|.....|...........|||..:.|..:|.
  Fly   608 PVIYQRERLPLLDHDHN------QIFYLGYAQLYCTDYPETVERFDELPEQLRVNTALSNSQQFA 666

  Fly   636 DTFECKATSQMNPVNKCHIW 655
            :.:.|....::|...||.::
  Fly   667 NAYGCSREEKLNARFKCTLY 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	158/710 (22%)
Nepl15	NP_651098.2	M13	56..684	CDD:341056	158/708 (22%)