Protein Alignment Nep6 and Nepl13

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 759
• Identity: 170/759 - (22%)
• Similarity: 276/759 - (36%)
• Gaps: 190/759 - (25%)

  Fly    19 LLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNW--YS---------NTSQRILGAHDMRSKW 72
            |::...|.|.|:.::...|    ||.:|.:||||.|  |.         :|:|::     |.:|.
  Fly    51 LVRQKIATDVQKYMNLSAD----PCTDFFEYACGQWGRYHKRQLRPDELSTAQQL-----METKI 106

  Fly    73 VANLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCCLL----SGQSIRTYTDALSRSGAN 133
            ...|:..|.:.|......:.:|.  :..|:..::...|..|:.    :.:..|.....|..:|.
  Fly   107 SEQLQQLLTQPLPPQHHPNGYSG--ASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGG- 168

  Fly   134 FPLLANHTGGSF----DWVLANAAL-RTYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLGRD- 192
               |.|....::    .||.....| |.||...|..|.:..|.|:......|...||..::..:
  Fly   169 ---LRNVPNSNWQHNRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEH 230

  Fly   193 ------------DELNEFLYQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLV 245
                        ||:.|.:.|:..:.|....|:....||..|..::.||..|.|.:   .||.
  Fly   231 CNALATRGAQVRDEVYELVQQQVTENLRDWFGMDTGEAARFAGDIIRFEFELCKQM---GEQD-- 290

  Fly   246 LRKPQ------------------------------SLKDLESQL-PRLELKRYFETILEGIDWDS 279
            ::||:                              :|.:|.|:: ..|:.|...|.|||. .:.|
  Fly   291 IQKPEEEFPPAIQAQIYGARSRTGQERLRRQKGGMTLTELTSEMGNHLDFKMLVEVILES-QYPS 354

  Fly   280 KTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFELRLHDDDKLGNQRNHCLEQLRKL 344
            :..|  ...:|::.:.|.:  ..::.:.:..::|  ..|..||....::....:...|::..::|
  Fly   355 QVYL--RSPEYVKHVVRTV--KANNRITVGGYIL--YVALNELNQPPEEAPSQRARQCVQVTQRL 413

  Fly   345 MPGQLGRLQMQLVLGESYQD--VYDTAIQQIAVLFRD----LKQQFELVLNETEVFNEDLVTRNL 403
            .|         .||||.:|.  ..|.|...:..:|.|    |::||.:     |..:|:  .|..
  Fly   414 FP---------QVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQFHV-----EWMDEN--DRRA 462

  Fly   404 ARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDANLLQLSLS-------QAKLEYR--------- 452
            ||.:|...|:..|..|              :.|...||...|       :..|:||
  Fly   463 ARTRLSQYRVSLPDYQ--------------SLDLTDLQFQKSEDYWRRLEIALKYRSHQQFEALR 513

  Fly   453 -QVFGEPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAH 516
             ..||:....:  |...|.|....:...:.:..||:..|.......|...     .|.||:.||.
  Fly   514 GNDFGQDADGL--DAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLK-----YALLGHRLAS 571

  Fly   517 EMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGC----YLGVRYS------NATLTVNENI 571
            .:|.|||.:|.|   ....|..||:...:..:...:.|    |....|:      ||| .:.|.|
  Fly   572 ALVQAFDDEGWN---NHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNAT-RLREII 632

  Fly   572 ADTEGLRLALDTY-------RHR------------SGATNLRTFFVAFAQNWC------GTVAST 611
            ||..||.||.:.|       .|:            ...||.:.||:.|||..|      ..:..:
  Fly   633 ADGSGLNLAFNAYLAWLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDS 697

  Fly   612 SGLSQHAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            ..|.||......||..:.|..|||..|.|...:.||..:||.::
  Fly   698 MPLMQHTPERWDVNGPLSNSAEFGREFGCALGTPMNSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	164/734 (22%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	164/737 (22%)