Protein Alignment Nep6 and Nepl12

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 171/769 - (22%)
• Similarity: 293/769 - (38%)
• Gaps: 196/769 - (25%)

  Fly    10 RLVVILGVMLLKLAAAQDCQQQ--LDNDTDAE-----------------------------VKPC 43
            :|:.::.:.::..|...||:.:  :|...:::                             |:||
  Fly     7 KLISLMLLWVIVAAVLTDCEARSLVDRSENSDSNGSSTNRSAAEYQLQEYAEFMKSYMNQSVEPC 71

  Fly    44 ENFHQYACGNW-------YSNTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTT 101
            |||::|||||:       ||..|:..||          ::...||...|:.......:...:|::
  Fly    72 ENFYEYACGNYRNVKPDRYSPGSRSNLG----------DVTYTLIDITEQLLGRMDLAEALNVSS 126

  Fly   102 STAQLGTLYRCCLLSGQSIRTYTDA------LSRSGANFPLLANHT--GGSFDWVLANAALRTYG 158
            ..|.....|..||  |.::..:..|      |.||...||.:....  ..:|:|:..:|.|..||
  Fly   127 ELAVAQRFYNACL--GANLHPFNAADPAYLSLIRSIGGFPAVDGDAWKASNFNWINMSAHLANYG 189

  Fly   159 AQGLWRLLVKDNWQSADQRIFYMLPP--KFDLLGRDD----------------ELNEFLYQRYLK 205
            |.|    |:::..|     :.|...|  |...||.|.                .|||.....||:
  Fly   190 ANG----LIRETLQ-----LRYPFEPYTKLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLR 245

  Fly   206 ILLLELGL---RVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDLESQLPRLELKRY 267
                ..||   |:|.|  :|.....:..:|:  :|...|    :..|..:|.:   .|:.|.  |
  Fly   246 ----AFGLPEDRIREA--IAGVFAFWRDALE--IPPQCE----VFDPYRIKRV---FPQSEY--Y 293

  Fly   268 FETILEGIDWDSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFELRLHDDDKL-- 330
            :.....|:...:|   |..|..|:: |.::.|.|..   .::.:|.::|...|      |.||
  Fly   294 YNISWSGLHSTNK---LFCDFYYVE-LDKVCARHRK---AVANYLAMKLLYRF------DPKLKA 345

  Fly   331 -GNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLFR---------DLKQQFE 385
             ..|||:|...|.:.|.....:|.|.....|:.:......::::....|         |.:.:..
  Fly   346 PRYQRNYCSVTLYQSMRFLFNKLYMANNFSEAKRLEMSEMVRELRKSLRKALEDADWLDAESRAR 410

  Fly   386 LVLNETEV------FNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDANLLQLSL 444
            .:|.|:.:      |.:|.::..:.|: :.:::::..|..:.            |.:...|.:.:
  Fly   411 ALLKESRIQPRIGSFQDDALSDRIIRE-INSLKVIEDRYAET------------NINLQHLVVQI 462

  Fly   445 SQ-AKLEYRQVFGEPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSA 508
            :: :...::::..:.........|.|.|.|....|.|.:..|::..|:.|:...      ..|..
  Fly   463 NRFSSRHFQELTNDTKPQKILTGLQVGAGYYTPDNSINVMAGVVEPPIYQRHLP------ISLKF 521

  Fly   509 G-LGYILAHEMVHAFDLDGLNYDATGQLAN--GQWSARAIIRFGLRAGCYLGV----------RY 560
            | ||:|:.||::|.||.....:|..|.:.:  .:.|.:|:..   ||.||:..          |.
  Fly   522 GTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEISQQALED---RAECYMDYYGKYQVPEISRR 583

  Fly   561 SNATLTVNENIADTEGLRLALDTYR-HRS------------------GATNLRTFFVAFAQNWCG 606
            .|...|::|||||..|||.||..|| ||.                  ..|..:.||:.|||.:|.
  Fly   584 VNGKTTLDENIADNSGLRQALTAYRSHRQQLLEHPGQERISDAMPGLDLTPEQLFFLGFAQLFCS 648

  Fly   607 TVAST---SGLSQ-HAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNK-CHIW 655
            .....   .|||. |.....||..|:.|..:|...:.|...|.|.|..| |.:|
  Fly   649 HYEEEHYWKGLSDVHTFDQFRVLGVLSNSEDFFHAYNCSVGSGMRPGAKTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	164/704 (23%)
Nepl12	NP_649924.1	M13	68..700	CDD:341056	164/704 (23%)