Protein Alignment Nep6 and Nepl11

DIOPT Version :9

• Sequence 1: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 686
• Identity: 137/686 - (19%)
• Similarity: 229/686 - (33%)
• Gaps: 204/686 - (29%)

  Fly    37 DAEVKPCENFHQYACGNWYSNTS-------QRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFS 94
            |...:||::|:.|.|.: .:|.|       |.:|...|:..  :.:::||||.:.:...|.....
  Fly    40 DTSKQPCQDFYGYVCSH-SANLSETGRQRFQSLLKETDVAQ--LMDMELQLINFFKSCESGRGVE 101

  Fly    95 ANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLL-------ANHTGGSFDWVLANA 152
            |                   |.|..       |.|....:|.|       :..|..:..|:....
  Fly   102 A-------------------LKGSQ-------LYRQSGGWPSLEPNKVNASQRTNQTQRWLGLLG 140

  Fly   153 ALRTYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLGRDDELNEFLYQRYLKILLLELGLRVRR 217
            .....||...:...|.   ..:::|:..:.|..    .|.:.|.:|  ::.:..:|...|:...|
  Fly   141 YFHEVGAPYFFETSVT---MQSNKRLVVLQPDG----TRRNTLRKF--EQRVGEVLQSFGIEQSR 196

  Fly   218 AALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDL---ESQLPRLELKRYFETILEGIDWDS 279
            |.:.|.::::.|:|.:.::..|..:..|.....:.|.:   .:.|.||:...||..:|.|
  Fly   197 AHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGG----- 256

  Fly   280 KTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLP---AYFELRLHDDDKLGNQRNHCLEQL 341
            ||                       |....|.::.|||   .||.|.         |....:..|
  Fly   257 KT-----------------------PQASDTIVVKQLPRLVEYFALL---------QNTSMVRLL 289

  Fly   342 RKLMPGQLGRLQMQLV------LGESYQ-DVYDTAIQQIAVLFRDLKQQF-ELVLNETEVFNEDL 398
            ..:....|    |.:|      |.|:|. |:|...:|::.....:|.|.: ||
  Fly   290 NWIWTDYL----MDIVDADCHQLSETYAGDLYAHVVQRVTANRVELAQMYSEL------------ 338

  Fly   399 VTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCDANLLQLSLSQAKLEYRQVFGEPV-TSV 462
                                     |...|.||||:...:.:....|      ||..|..: |::
  Fly   339 -------------------------GKAYTDQLGGSVWIDEISRQSS------RQFLGNIMHTTL 372

  Fly   463 PADPLSVNAYYRLKLNRIELPLGLMATPLIQ----------QQCSKEADTRAKLSAGLG------ 511
            ..|.....||:.:.|.|..|...|......|          ||..:.|...|.::|.||
  Fly   373 NGDERLDAAYHSILLGRRSLYRNLEKLRKFQRTRRLASHSAQQVRRYAQMFAPVNAFLGQHNLST 437

  Fly   512 ---YILAHEMVHAFDLDGLNYDATGQLANGQW-SARAIIRFGLRAGCYLGVRYSNATLTVNENIA 572
               |:|..|    |....|....:.....|.| |:.:..||.:...| :| :.:||...:...:|
  Fly   438 PLNYLLLGE----FFSRSLVAAGSSSRTQGAWRSSDSERRFAIFQQC-VG-KQTNAIDLLLSLLA 496

  Fly   573 DTEGLRLALDTYRH----------------RSGATNL---RTFFVAFAQNWCGTVASTSGLSQHA 618
            .    |.||..|..                .:|::.:   |.|||......|   .|..|..|..
  Fly   497 Q----RQALSAYGQWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDC---RSELGALQQD 554

  Fly   619 GHAERVNNVVGNMPEFGDTFECKATSQMNPVN-KCH 653
            ...:..:..:.|.|||.:.|.|:....:.|.: :|:
  Fly   555 RKRQVTHATLRNSPEFLEAFRCRPGDVLYPQDQRCN 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	137/686 (20%)
		M13	40..653	CDD:189000	135/681 (20%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	135/678 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910