Protein Alignment Nep6 and Nep3

DIOPT Version :9

• Sequence 1: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001245775.1
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 175/708 - (24%)
• Similarity: 298/708 - (42%)
• Gaps: 130/708 - (18%)

  Fly    37 DAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQ-----LIRYLEESSSTDSFSAN 96
            |..|.||::|:.|:|..|..|..     ..:.:|.|....||:     :||.:.|..: .||.::
  Fly   120 DVTVDPCDDFYGYSCNQWIKNNP-----IPEGKSTWGTFGKLEQMNQLIIRNVLEKPA-KSFKSD 178

  Fly    97 TSVTTSTAQLGTLYRCCLLSGQSI-----RTYTDAL--------SRSGANFPLLANHTGGSFDWV 148
                 :..:....|..||.:.:.:     :...|.|        ::||.|   :||.|.|....:
  Fly   179 -----AERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYN---VANWTMGHTLKI 235

  Fly   149 LANAALRTYGAQGLWRLLVKDNWQSADQRIFYM------LPPKFDLLGRDDE----LNEFLYQRY 203
            |.|    .|....|:...:.::.:::.:.:..:      ||.......:.|.    |||::  .|
  Fly   236 LHN----KYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYI--EY 294

  Fly   204 LKILLLELGLRVRRAALLAEKLVAFEKSLQKL-LP-NDAEQTLVLRKPQSLKDLESQLPRLELKR 266
            :..:.:.||.....|......::.|||.|..: :| .|......:..|..|:.|....|.|....
  Fly   295 MTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTD 359

  Fly   267 YFETILEGID---WDSKTLLLVADLDYLQGLQRLL--AEHTSD-PMVLSTWLLLQL--------- 316
            :|:..::.:.   .|.:.:::.|. |:|:.|..::  .|.|.: .:.|:.:|:.|.
  Fly   360 HFDNAMQMVGRRVTDDEVVVVYAP-DFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLS 423

  Fly   317 ----PAYFELR--LHDDDKLGNQR--NHCLEQLRKLMPGQLGRLQM-QLVLGESYQDVYDTAIQQ 372
                .||..:|  |...|  |.:.  .:|:.....::...:|.:.: |...|||    ...|.|.
  Fly   424 KPFRDAYKGVRKALMGSD--GGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGES----KPAAEQM 482

  Fly   373 IAVLFRDLKQQFELVL-NETEVFNEDLVTRNLARDK---LRAMRLLTPRLQDPINGGPGTPQLGG 433
            ||    ::::.|::.| |.|.|   |..||..|.:|   :..|......:.||:.......:|..
  Fly   483 IA----EIREAFKMNLQNLTWV---DKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNI 540

  Fly   434 NCDA---NLLQLSLSQAKLEYRQVFGEPV--TSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQ 493
            ..:|   |.:|:::...|...::: .:||  |:....|.:|||||....|:|..|.|::.||...
  Fly   541 TPNAYFENNIQVAIYNLKSNLKRL-DQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFD 604

  Fly   494 QQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGC---- 554
            ....|..:..|     :|.::.||:.||||..|..||..|.: |..|.:::|.||..::.|
  Fly   605 INNPKSLNFGA-----MGVVMGHELTHAFDDQGREYDKFGNI-NRWWDSKSIERFNEKSECIARQ 663

  Fly   555 YLGVRYSNATL----TVNENIADTEGLRLALDTYRHRS-------------GATNLRTFFVAFAQ 602
            |.|.:.:..||    |:.|||||..||:.|...|:...             ..|:.:.|||:|||
  Fly   664 YSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQ 728

  Fly   603 NWCGTVASTSGLSQ-----HAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            .||.:....:.|.|     |:....||...:.||.||.:.|:||...:|||..||.:|
  Fly   729 VWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	174/706 (25%)
		M13	40..653	CDD:189000	172/701 (25%)
Nep3	NP_001245775.1	M13	123..784	CDD:189000	172/701 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454935
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850