Protein Alignment Nep6 and frma

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 715
• Identity: 157/715 - (21%)
• Similarity: 251/715 - (35%)
• Gaps: 208/715 - (29%)

  Fly    11 LVVILGVMLLKLAAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVAN 75
            |.:|:|::::::.:    ..|.|        ||:||::.|||||  :.|...........:...|
  Fly     8 LELIVGLLVVQVKS----HPQAD--------PCQNFYKVACGNW--SASHATDSYESFMDRLDYN 58

  Fly    76 LKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCC---LLSGQSIRTYTDALSRSG-ANFPL 136
            .:.:|...|:.....|.       .....||...|..|   |...|.:|.....:.... .|..|
  Fly    59 YQEKLADLLDNEREDDE-------PHFLQQLRNFYTACRKPLSQDQVLRILEHLIVMENIQNEEL 116

  Fly   137 LANHTGGSFDWVLANAALRTYGAQGLWRLLV--KDNWQSADQRIFYMLPPKFDLLGRDDELNEFL 199
            ....|......||.:  |.......:|:.|:  :.:|.........:....||.|........|.
  Fly   117 SVGLTAAFRLQVLID--LNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPFP 179

  Fly   200 YQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDLESQLPRLEL 264
            ::.|.          .|..:.|.||::::...      :|...:         .||.:::|...:
  Fly   180 FKEYY----------WRELSELEEKIMSYGSE------DDGFDS---------GDLVTRIPPFWM 219

  Fly   265 KRY------FETILEGIDW-DSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFEL 322
            ..:      :|.:.:...| |.|....:  |.|:....:|:||..|    ..:|
  Fly   220 MPWPNGNITYENLSQMAHWLDIKANEFI--LTYIYMRLKLVAEGVS----TESW----------- 267

  Fly   323 RLHDDDKLGNQRNHCLEQLRKLMPGQLG--------RLQMQLVLGESYQDVYDTAIQQIAVLFRD 379
              |.|      |:.|.||.|:::.....        ||:.:.||    ||:           |.:
  Fly   268 --HID------RDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVL----QDI-----------FAE 309

  Fly   380 LKQQF--ELVLNETEVFNEDLVTRNLARDKLRAMRL---LTPRLQDP---------------ING 424
            |||:|  :|:.|..   |....|::....||:.|||   :.||....               :|.
  Fly   310 LKQRFGQKLLANRN---NFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNA 371

  Fly   425 GP--GTPQLGGNCDANLLQLSLSQAKLEYRQ----VFGEPV------------TSVPADPLSVNA 471
            ..  |...:|         |:.|::..:|.|    |||..:            |.|.......:|
  Fly   372 SDYFGNLHIG---------LNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASA 427

  Fly   472 YYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLS----AGLGYILAHEMVHAFDLDGLNYDAT 532
            :|.:|.|.:.:||.|:..|..         |..:.|    :.||:||.||:.|.||.:|:.:.:.
  Fly   428 FYIVKQNMLIVPLSLLEPPFY---------THGQPSILTYSALGFILGHELSHGFDSEGMTFSSH 483

  Fly   533 GQLANGQWSARAI-------IRFGLRAGCYLGVRYSNATLTVNENIADTEGLRLALDTY------ 584
            |.      .:.|:       .||....|| |..|:.....   |..||..||.||...|
  Fly   484 GV------GSSAVDRELDRNPRFQQELGC-LRRRFGRKRY---EKFADASGLELAYSAYFDTAQT 538

  Fly   585 ---RHRSG---ATNLRTFFVAFAQNWCGTVASTSGLSQ---HAGHAERVNNVVGNMPEFGDTFEC 640
               |:||.   .|..:.||..|||.:|    |...|.|   |....:|||:.|.:...|.:.|.|
  Fly   539 DHKRNRSAEELVTQKQQFFHNFAQFFC----SDKELLQAHDHGSDRKRVNDAVAHFEPFREAFSC 599

  Fly   641  640
              Fly   600  599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	152/686 (22%)
frma	NP_572226.2	GluZincin	25..601	CDD:472708	153/694 (22%)