Protein Alignment Nep6 and Kel

DIOPT Version :9

• Sequence 1: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 742
• Identity: 168/742 - (22%)
• Similarity: 258/742 - (34%)
• Gaps: 236/742 - (31%)

  Fly    42 PCENFHQYAC--GNWYSNTSQRILGAHDMRSKWVANLKLQLIRYLE-------ESSSTDSFSANT 97
            ||.:|..:||  .|..||:.|.:  |.:.:|:        |.:.||       ||....:|.
  Rat    80 PCTDFFSFACEKANGTSNSFQAL--AEENKSR--------LWKLLEAPGSWHLESGEEKAFQ--- 131

  Fly    98 SVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPL--LANHTGG---SFDWVL--ANAALR 155
                       .|..|:        .|||:..||.. ||  :....||   |.:|..  .|..||
  Rat   132 -----------FYNSCM--------DTDAIEASGTG-PLVQIIKELGGWNISGNWTFFDFNQNLR 176

  Fly   156 ----TYGAQGLWRLLVKDNWQSADQRIFYMLPPKFDLLGRDDE--------LNEFLYQRYLKILL 208
                .||....:|..:..:.......|..:..|:||:|.:.|:        |.|  |..||..|.
  Rat   177 LLMSQYGHFPFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQILRE--YVTYLNRLG 239

  Fly   209 LELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDLESQLPRLELKRYFETILE 273
            ..||...:.|...|...:.|...|.:.|           :||..:..:.:|..:......:.:..
  Rat   240 TLLGSNPQEAQQHASWSIVFTSRLFQFL-----------RPQQQQQAQDKLFHVVTIDALQEMAP 293

  Fly   274 GIDW--------------DSKTLLLVADLDYLQGLQRLLAE----HTSDPMVLSTWLLLQL---- 316
            .|||              .|:| |.|.|||||:.:.:|:.|    |:.   ::.::::|.|
  Rat   294 AIDWLSCLQAIFTPMSLSPSQT-LQVHDLDYLRNMSQLVEEGLLNHSE---IIQSYMILGLVDTL 354

  Fly   317 -PA----YFELRLHDDDKLGNQRNH-----------CLEQLRKLMPGQLGRLQMQLVLGESYQDV 365
             ||    :.|.|.....||...:..           |:||........|..|.:....|.|
  Rat   355 SPALATKFQEARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPS---- 415

  Fly   366 YDTAIQQIAV-LFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTP 429
                |:..|: ||.::|....:.|.:....:|:  ||..|.:||..:::           ..|.|
  Rat   416 ----IRSAAMELFAEIKDAVIVRLKKLSWISEE--TRKEALNKLTQLQV-----------EMGAP 463

  Fly   430 QLGGNCDANLLQLSLSQAKLEY-----------------RQVFGEPVTSV---------PADPLS 468
            :..         |....||.||                 |.:.|..|.|.         ...|.|
  Rat   464 KRA---------LKTEMAKQEYSDIQLGPSFLQSFLSCVRSLQGRKVRSFLQPFPYHRWQKSPWS 519

  Fly   469 VNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATG 533
            |:|||.:..:.:..|.||:..|...     ....||.....:|.|:||:::|.|
  Rat   520 VSAYYSVPDHVVVFPAGLLQPPFFH-----PGYPRAVNFGAVGSIMAHKLLHIF----------- 568

  Fly   534 QLANGQWSARAIIRFGLRAGC-------------YLGVRYS----------NATLTVNENIADTE 575
                        .:|.|..||             .|..||:          |.:.|:.||.||..
  Rat   569 ------------FQFLLPGGCPACDTRALQEALLCLEHRYAAFPLPSMSSFNGSHTLLENAADIG 621

  Fly   576 GLRLALDTYR----HRSGATNL--------RTFFVAFAQNWCGTVASTSGLSQHAGHAERVNNVV 628
            |:.:|...||    .|:|...|        :.||.::||..|..:.|......|:....||:..:
  Rat   622 GVAIAFQAYRKRITERTGELTLPNQELSPYQLFFRSYAQVMCRELISQDPQDTHSPPRLRVHGPL 686

  Fly   629 GNMPEFGDTFECKATSQMNPVNKCHIW 655
            .|.|:|...|.|.:.|.:||..:|.:|
  Rat   687 SNSPDFAKHFLCPSGSLLNPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	167/740 (23%)
		M13	40..653	CDD:189000	166/738 (22%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	167/740 (23%)
		M13	78..711	CDD:189000	166/738 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344479
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810