Protein Alignment Nep6 and Mme

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_036740.1
• Gene: Mme / 24590
• RGDID: 3098
• Length: 750
• Species: Rattus norvegicus
• Alignment Length: 771
• Identity: 169/771 - (21%)
• Similarity: 304/771 - (39%)
• Gaps: 171/771 - (22%)

  Fly     5 LSSITRLVVILGVMLLKLAAAQD---CQQ--------QLDNDTDAEVKPCENFHQYACGNWYS-- 56
            ||.:..|:.|:.|.::.|.|..|   |:.        :|..:.||..:||.:|.:||||.|..
  Rat    31 LSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDASAEPCTDFFKYACGGWLKRN 95

  Fly    57 ---NTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCCL---- 114
               .||.|......:|.:    |::.|...|:|..:.|        ..:..:..||||.|:
  Rat    96 VIPETSSRYSNFDILRDE----LEVILKDVLQEPKTED--------IVAVQKAKTLYRSCINESA 148

  Fly   115 ---LSGQSIRTYTDALSRSGANFPLLANH---TGGSFDWVLANAALR---TYGAQGLWRLLVKDN 170
               ..||.:.|....:    ..:|:.:.:   |.|: .|....:..:   .||.:.|....|..:
  Rat   149 IDSRGGQPLLTLLPDI----YGWPVASQNWEQTYGT-SWTAEKSIAQLNSKYGKKVLINFFVGTD 208

  Fly   171 WQSADQRIFYMLPPKFDLLGRDDELNEFLYQR----YLKILLLELGL-RVRRAALLAEKLVAFEK 230
            .:::.|.|.:...|:..|..||......:|:.    |:..::....| |..:...:.|..::.|
  Rat   209 DKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQRLPIDENQLSLE- 272

  Fly   231 SLQKLLPNDAEQTLVLRKPQSLKD---LESQLPRLELKRYFETILEG--IDWDSKTLLLVADL-- 288
             :.|::..:.|......||:...|   |.:::...:|:..|...:.|  ..|.:.|..:::.:
  Rat   273 -MNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEINGKPFSWSNFTNEIMSTVNI 336

  Fly   289 -------------DYLQGLQRLLAEHT-SDPMVLSTW-LLLQLPA-----YFELR------LHDD 327
                         :||..|:.:|.::: .|...|.:| .::.|.:     |.|.|      |:..
  Rat   337 NIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGT 401

  Fly   328 DKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLF-----------RDLK 381
            .........|...:...|...:|||.::.......:.|.:..|.||..:|           .:.|
  Rat   402 TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETK 466

  Fly   382 QQFE---LVLNETEVFNEDLVTRNLARDKLRAMRL-LTPRLQDPINGGPGTPQLGGNCDANLLQ- 441
            ::.|   |.:.|...:.:|:::.   .:||....| |..:.::...              |::|
  Rat   467 KKAEEKALAIKERIGYPDDIISN---ENKLNNEYLELNYKEEEYFE--------------NIIQN 514

  Fly   442 LSLSQAK--LEYRQ-------VFGEPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCS 497
            |..||:|  .:.|:       :.|..|         |||:|....|:|..|.|::..|....:.|
  Rat   515 LKFSQSKQLKKLREKVDKDEWISGAAV---------VNAFYSSGRNQIVFPAGILQPPFFSARQS 570

  Fly   498 KEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYL------ 556
            ...:     ..|:|.::.||:.|.||.:|.|::..|.|.: .|:.::...|..::.|.:
  Rat   571 NSLN-----YGGIGMVIGHEITHGFDDNGRNFNKDGDLVD-WWTQQSANNFKDQSQCMVYQYGNF 629

  Fly   557 -----GVRYSNATLTVNENIADTEGLRLALDTYRH---RSGATNL---------RTFFVAFAQNW 604
                 |.::.|...|:.|||||..|:..|...|::   ::|...|         :.||:.|||.|
  Rat   630 TWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVW 694

  Fly   605 CGTVASTSGLSQ-----HAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            |||......::.     |:....|:...:.|..||.|.|.|:..|.|||..||.:|
  Rat   695 CGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	155/721 (21%)
Mme	NP_036740.1	Stop-transfer sequence. /evidence=ECO:0000255	16..23
		M13	79..748	CDD:341056	155/719 (22%)