Protein Alignment Nep6 and nep-6

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 738
• Identity: 161/738 - (21%)
• Similarity: 274/738 - (37%)
• Gaps: 220/738 - (29%)

  Fly    31 QLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQ---------LIRYLEE 86
            ||.|..|..|.||::|::.|||. ||.        |:     |||.:||         :..:|.:
 Worm    96 QLLNFQDPSVDPCQDFYKAACGK-YSE--------HE-----VANRRLQKKDIIIQRMIKNFLLK 146

  Fly    87 SSSTDSFSANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANHTGGSFDWVLAN 151
            :.:::|.|.|.        :..:||.|                            .|..:..:.|
 Worm   147 NETSESKSENV--------MRQVYRTC----------------------------EGLKNEEIFN 175

  Fly   152 AALRTYGAQGLWRLLVKD-----NWQSADQRIFYMLPPKFDLLGRDDE----LNEFLYQ------ 201
            |.::|     .:|.|.||     :|.:||:..              ||    |||.|..
 Worm   176 ANMKT-----AFRELFKDIQKIGSWPAADKNW--------------DETKLNLNEMLLNIVKLGS 221

  Fly   202 --------RYLKILLLELGLRVRRAALLAEKL--VAFE----KSLQ---KLLPNDAEQTLVLRKP 249
                    |..::..||:...:.|:..::...  :.|:    ..||   .::.:|.|..:.|.:.
 Worm   222 SNFGLFQIRPTEVPFLEVAPDMARSPKVSANFQQIIFDILEKNGLQPDENVIADDVEDYITLEET 286

  Fly   250 QS------------LKDLESQLPRLELKRYFETILEGIDWDSKTLLLVADL-------------D 289
            .|            ...|::|:|.|:|::..|.::.    .::..|||..:             |
 Worm   287 LSQYAYDYNAEKVQFSKLQAQVPSLKLEKIIEEMMN----PNRKKLLVTKVKPRMVAHKHSLFFD 347

  Fly   290 YLQGLQRLLAEHTSDPMVLSTWLLLQLPAYFE-----LRLHDDDKLGNQRNHCLEQLRKLMPGQL 349
            ....|::||  .::....|:.:|:..   |.:     |.:||:  :..:|| |    .||:...|
 Worm   348 EKMNLEKLL--KSTPKRTLANYLIFY---YMDHAMNGLSVHDN--VIKKRN-C----EKLVIEYL 400

  Fly   350 GRLQMQLVLGESYQDVYDTAIQQIAVLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLL 414
            .:..:::.:...::......:.::|   .:.|:.|..:|.|:.....|  ::..|..||..|..:
 Worm   401 PKASLRVFVRNHFEKGNLKIVDEMA---EETKKSFIEMLQESTWLGAD--SKKNAILKLEKMGKM 460

  Fly   415 TPRLQDPINGGPGTPQLGGNCDANLLQLSL-----------SQAKLEYRQVFGEPVTSVPADP-- 466
            .        |.|...:..|..|.....|.|           ...:....|.........|.||
 Worm   461 I--------GYPKEFEKKGALDKMFETLKLLPKDTLYGILKKIGRFHMEQGIEFVALETPMDPVL 517

  Fly   467 --LSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNY 529
              |..||:|..: |.:...:|.|..||......|..:.     |..|.|||||..|.||..|:..
 Worm   518 PVLMTNAFYTDR-NHLSFLVGYMDDPLFDATYPKYVNI-----ALTGNILAHETSHGFDTAGIKR 576

  Fly   530 DATGQLANGQW-SARAIIRFGLRAGCYLGVRYS-----------NATLTVNENIADTEGLRLA-- 580
            |..|::.:  | ....:..:|.:..|.:. :|:           |.|.|:||.:||..|:.:|
 Worm   577 DENGEVRS--WMKPEDLKEYGKKTQCLVD-QYNEYDDPVFGKNLNGTTTLNEMVADMIGVTVAWK 638

  Fly   581 ----LDTYRHRS--GATNL---RTFFVAFAQNWCGTVASTSGLSQ----HAGHAERVNNVVGNMP 632
                ||:.:.:.  |..|.   :.:|.|.|.::|....:||.:.:    |.....|||.:..|||
 Worm   639 VFEKLDSSKEQKVIGFENENIDKLYFRAAALDFCSLPPTTSLVEELTRVHPTGNFRVNGIFSNMP 703

  Fly   633 EFGDTFECKATSQMNPVNKCHIW 655
            :|...|.|...|.|||..:|.|:
 Worm   704 QFATAFNCPEGSPMNPKTRCSIF 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	155/725 (21%)
nep-6	NP_494537.1	M13	105..724	CDD:341056	155/725 (21%)