Protein Alignment Nep6 and nep-10

DIOPT Version :9

• Sequence 1: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 141/706 - (19%)
• Similarity: 269/706 - (38%)
• Gaps: 163/706 - (23%)

  Fly    31 QLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIR-YLEESSSTDSFS 94
            :|.|..|..|.||::|:|:.||.:|.:::   :|...|.:|  .:...:||| :|.::.::.|.|
 Worm    88 ELHNYKDPSVDPCQDFYQHFCGKFYEHSA---IGQGRMATK--RSTLSKLIREFLLKNKTSTSKS 147

  Fly    95 ANT--SVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANHTGGS------------- 144
            .||  .|.....:|..:.....:..|::......:.:.|| :|:|.....||
 Worm   148 ENTMKQVYAKCRELQKISDLNSIPPQALLDIFSDIKKIGA-WPVLDKDWDGSKFNLNEMLRQLVN 211

  Fly   145 ----------FD-----WVLANAALRTYGAQGLW--------RLLVKDNWQSADQRIFYMLPPKF 186
                      ||     :||....|:    ||:.        :::::.|....||
 Worm   212 LGETHLGFFHFDFIARPYVLIKPPLK----QGVQKSVLEKVVKMILEANEIKMDQ---------- 262

  Fly   187 DLLGRDDELNEFLYQRYLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQS 251
               |..::|:|:          .||..|::     .:||....:|:..|||:       :|:...
 Worm   263 ---GFSEDLDEY----------FELSNRIK-----IDKLPRTSRSIVGLLPD-------VRRINF 302

  Fly   252 LKDLESQLPRLELKRYFETILEG-IDWDSKTLLLVADLDYLQGLQRLLAEHTSDPMVLSTWLLLQ 315
            ...:...:||.::.|:..|:.:. :.:.....:...:.::|..:.|     ::....|:.:|:..
 Worm   303 RGLILEMMPRSKMNRFLGTLFQKVVTYHHPLFVRDNETNHLDTIIR-----STSNRALANYLIFN 362

  Fly   316 LPAYFELRLHDDDK-----LGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTA-IQQIA 374
            .       :|...|     |.:.|..|    .|::..:|.|..:::.:    ::..|.. .:::|
 Worm   363 F-------IHSSIKFLTFGLKSDRERC----EKIVVQELPRPSLRVFM----RNCVDKGNREEVA 412

  Fly   375 VLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGT-----PQLGGN 434
            .|...:|:....::.|::.|...:..|.|.:.:.....:..|...||    |||     ..|..:
 Worm   413 KLTETVKENVLEMIRESDSFTPSVKKRVLKKVEAIGAIIGYPDHFDP----PGTLDKEYENLTLD 473

  Fly   435 CDANLLQLS--LSQAKLEYRQVF--GEPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQ 495
            ...:..::|  |.|.:|:::..|  |:...|.....|.|||:|..|.|.:.:....:..|.....
 Worm   474 ASDSYYKMSQKLHQLRLQHQMEFLAGQTPLSPSDQVLEVNAHYDSKDNALTVLAPFLDDPFFDST 538

  Fly   496 CSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYLGV-- 558
            ..:..:.     ...|:::.||..|:.|...|..|       |.:....:..:|.||.|.:..
 Worm   539 YPEYVNL-----IFTGFLIGHEFGHSIDPKILRRD-------GWYKTEDMTEYGKRAQCLIDQYD 591

  Fly   559 --------RYSNATLTVNENIADTEGLRLALDTYRHRSGA----------TNL-RTFFVAFAQNW 604
                    :..|.|..:.|.:.|..|..:....::....:          .|| :.:|...:..:
 Worm   592 NYDDPDHGKQMNGTYCIGEIVGDWVGRDVTWRAFKKMDLSKMQKLIGFEDKNLDQLYFRIQSLFF 656

  Fly   605 CGTVASTSGLSQ-----HAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            ||. .|...|.|     |.....|||.:..|||:|...|.|...|.|||..||.::
 Worm   657 CGP-RSMKSLEQLLSDPHPTEVFRVNGIYSNMPQFAKAFNCPIGSPMNPEKKCKMF 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	139/700 (20%)
		M13	40..653	CDD:189000	137/693 (20%)
nep-10	NP_494532.2	M13	97..709	CDD:189000	137/693 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920