Protein Alignment Nep6 and ecel1

DIOPT Version :10

• Sequence 1: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 189/766 - (24%)
• Similarity: 296/766 - (38%)
• Gaps: 189/766 - (24%)

  Fly    11 LVVILGVML-LK-LAAAQD------CQQQ---------LDNDTDAEVKPCENFHQYACGNW---- 54
            |.||||.|| || |:..||      ||::         :.|:.|..:.||.:|:.:|||.|
 Frog    67 LCVILGCMLVLKYLSMEQDVQCLEGCQERKAFMRASKFITNNIDPTISPCTDFYSFACGGWLRRH 131

  Fly    55 --------YSNTSQRILGAHDMRSKWVANLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYR 111
                    |..    |....:...:.:.:|.||.:|...:.|             :..::...::
 Frog   132 GIPEDKLIYGT----IAAIGEQNEEKLEHLLLQPVRRKHKGS-------------AERKVKEFFK 179

  Fly   112 CCLLSGQSIRTYTDALSRSGANFPLLANHTGGSFD--------WVLANAALRTYGAQG---LWRL 165
            .||    ::|.    :.|.||...|......|.:|        |.......:|.|...   .:.:
 Frog   180 SCL----NMRD----IDRLGARPMLQVIEDCGGWDLPEDPRTQWDFNELLYKTQGVYSTAVFFSM 236

  Fly   166 LVKDNWQSADQRIFYM------LPPKFDLLGRDDELNEFL--YQRYLKILLLELGLRVRRAALLA 222
            .|..:.:::.:.|..:      ||.:...||:|:|..:.|  |:.:::.:|..||  |......|
 Frog   237 TVSLDDKNSSRYIIRIDQDGLTLPERTLYLGQDEESIKVLEAYKVFMQTILSLLG--VENVQKKA 299

  Fly   223 EKLVAFEKSLQKLLPNDAEQTLVLRKPQS-------LKDLESQLPRLE----LKRYFETILEGID 276
            |:::..|:.|..:..::.:.   :|:..|       |..|:...|.|.    |.|.|.|   ...
 Frog   300 EEILHLEQHLSNITISEFDD---MRRDISTMYNKVTLAQLQQITPHLNWKNLLNRIFHT---NFP 358

  Fly   277 WDSKTLLLVADLDYLQGLQRL--------------------LAEHTSDPMVLSTWLLLQLPAYFE 321
            .|.:.::|..  ||:|.:..:                    |:||.|.|.         ..|..|
 Frog   359 EDEEVVVLAT--DYMQKVSEMIRSTPASVLHNYMLWRIVVVLSEHLSTPF---------RDAIHE 412

  Fly   322 L--RLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESYQDVYDTAIQQIAVLFRDLKQQF 384
            |  .:...:|.......||.|..|.....||.|.::    |.:.......:||   |..::|...
 Frog   413 LSKEMEGSEKQAELTKVCLTQANKHFGMALGALFVE----EYFSSSSKAKVQQ---LVENIKHIL 470

  Fly   385 ELVLNETEVFNEDLVTRNLARDKLRAMR--------LLTPRLQD-----PINGGPGTPQLGGNCD 436
            :..|.|.:..  |..|:..||:||:.|.        ||.|...|     .:|.......:
 Frog   471 DYRLEELDWM--DTETKQAAREKLKHMMVMIGYPDVLLQPESMDKEYEFEVNEKTYFKNI----- 528

  Fly   437 ANLLQLSLSQAKLEYRQVFGEPVTSVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQCSKEAD 501
            .|.::.|:..|....||...:....:|  |.::||||....|::..|.|::...|.      :.|
 Frog   529 LNSIRYSIKMAVRRIRQEVDKSAWLLP--PQALNAYYLPNKNQMVFPAGILQPTLY------DPD 585

  Fly   502 TRAKLS-AGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYLGVRYSNATL 565
            ....|: .|:|.|:.||:.|.:|..|..|||.|.... .|:..:..:|..:|.|.:.: |.|.|:
 Frog   586 FPQSLNYGGIGTIIGHELTHGYDDWGGQYDANGNPIQ-WWTEDSYSKFLKKAECIVDL-YENFTV 648

  Fly   566 ---------TVNENIADTEGLRLALDTYRH------------RSGATNLRTFFVAFAQNWCGTVA 609
                     |:.|||||..||:||...|:.            |...|:.:.||:|||||||....
 Frog   649 YNQRVNGRTTLGENIADLGGLKLAYYAYQKWVRDNGPERPLPRLKYTHDQLFFIAFAQNWCIKRR 713

  Fly   610 STSGLSQ-----HAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            |.|...|     ||....||...|....|||..|.|...|.||||:||.:|
 Frog   714 SQSIYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHCPRNSPMNPVHKCSVW 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_572831.2	M13	40..653	CDD:341056	171/716 (24%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	171/716 (24%)