Protein Alignment Nep6 and mmel1

DIOPT Version :9

• Sequence 1: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_012821551.1
• Gene: mmel1 / 100145721
• XenbaseID: XB-GENE-991673
• Length: 765
• Species: Xenopus tropicalis
• Alignment Length: 778
• Identity: 164/778 - (21%)
• Similarity: 288/778 - (37%)
• Gaps: 240/778 - (30%)

  Fly    23 AAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYS-----NTSQRILGAHDMRSKWVANLKLQLIR 82
            |||:..|     :.|..::||.:|:|||||.|.:     .||.|......:|.:....||..|
 Frog    83 AAARIIQ-----NMDPTIEPCTDFYQYACGGWLNKHVIPETSSRYSIFDILRDEMEIILKGLL-- 140

  Fly    83 YLEESSSTDSFSANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANHTGGSFDW 147
            .:.:....|:|.          :...||:.|:  .:|:....|:|       |||...|... :|
 Frog   141 EMPDQEDRDAFK----------KAKILYKSCM--NESLIEQRDSL-------PLLELLTTVG-EW 185

  Fly   148 VLANAALRTYGAQGLWRLLVKDNW---------------------------QSADQRIFYMLPPK 185
            .:|:..         |....:.||                           :.:.:.|.|:..|.
 Frog   186 PVASTD---------WNGTKESNWSLEEKLSLLNYKFNKRVLVDIFVWNDDRESSKHIIYIDQPS 241

  Fly   186 FDLLGRDDELNEFLYQR----YLKILLLELGLRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVL 246
            ..:..||...|:..|||    ||:.:            :...::|..:::|.:      :.:||.
 Frog   242 LGMPSRDYYFNKGNYQRIREAYLQFM------------ITIARMVREDRNLTR------DDSLVQ 288

  Fly   247 RKPQSLKDLESQLPR--------------------LELKRYFETILEGIDWDS------------ 279
            .:...:.|||:.:.|                    ||.::.|  .|:..:|.|
 Frog   289 EEMTRVMDLETDIARATAPSEERNDVTLLYNKMTLLEFQQKF--ALDDFNWTSFIQGVMSSVNIQ 351

  Fly   280 ---KTLLLVADLDYLQGLQRLLAEHTSDPMV-LSTWLLLQLPAYFELRLHDDDKLGNQR------ 334
               :..::|....||..|:.:|:.:::..:. ...|.::........|.:.|.:...::
 Frog   352 LQAEEEVVVYGAPYLHQLKNILSNYSASTLQNYVVWRMVIDRVSSLSRRYKDARASYRKALYGTT 416

  Fly   335 ------NHCLEQLRKLMPGQLGRLQM-QLVLGESYQDVYDTAIQQIAVLFRDLKQQFELVLNETE 392
                  ..|:..:...|...:|.:.: :...|||.:.:.|        |...:::.|...|:|.:
 Frog   417 LEEARWRECVSYVNSNMENAVGAMYVKETFAGESKRMISD--------LINKVREAFIETLDELQ 473

  Fly   393 VFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQ--LGGNCD-----------------AN 438
            ..:|      .::||.|...|   .:::.|    |.|.  |....|                 .|
 Frog   474 WMDE------TSKDKAREKAL---SIKEQI----GYPDYILEDQNDKLDQETAALNFSEYQYFEN 525

  Fly   439 LLQLSLSQAKLEYRQVFGEPVT-------SVPADPLSVNAYYRLKLNRIELPLGLMATPLIQQQC 496
            :|::..|.|:...::: .|||.       :..||     |:|....|:|..|.|::..|...:.
 Frog   526 ILEILNSGAQKSLKKL-REPVDQDAWIIGAAVAD-----AFYSPNRNQIVFPAGILQPPFFNKH- 583

  Fly   497 SKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGCYLGVRYS 561
                ..:|....|:|.::.||:.|.||.:|.|:|..|.:.: .||..:.:.|..::.|.: .:|.
 Frog   584 ----QPQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFD-WWSNFSAMHFKDQSRCMV-YQYG 642

  Fly   562 NAT------------LTVNENIADTEGLRLALDTY-----RHRS-------GATNLRTFFVAFAQ 602
            |.|            :|:.|||||..|:|.|...|     ||..       ..|..:.||:.|||
 Frog   643 NYTWELAGGQNVSGIITLGENIADNGGVRQAYKAYLKWVERHGKEPKLPGLDLTYKQLFFLNFAQ 707

  Fly   603 NWCGTVASTSGLSQHAGHA----------ERVNNVVGNMPEFGDTFECKATSQMNPVNKCHIW 655
            .|||     |...::|.|:          .||...:.|...|.:.|.||..::|:||.||.:|
 Frog   708 VWCG-----SYRPEYARHSIKTDVHSPFKYRVMGSLQNFEAFAEEFNCKKGTKMHPVEKCRVW 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	159/764 (21%)
		M13	40..653	CDD:189000	157/757 (21%)
mmel1	XP_012821551.1	M13	95..763	CDD:341056	157/757 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110