Protein Alignment Pde9 and Pde7a

DIOPT Version :9

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: NP_112342.1
• Gene: Pde7a / 81744
• RGDID: 68391
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 352
• Identity: 98/352 - (27%)
• Similarity: 162/352 - (46%)
• Gaps: 23/352 - (6%)

  Fly   667 RFLEICDTTFSEEVRAALRLPA---FDSYEW----SDADVIHLMQTMFVELGFIEKFSIPVDTLR 724
            |.|.|.|..::.:.:..|....   ||.:.:    :...::.|...:|...|.||.|.:.:..||
  Rat   131 RSLNILDEDYNGQAKCMLEKVGNWNFDIFLFDRLTNGNSLVSLTFHLFSLHGLIEYFHLDMVKLR 195

  Fly   725 EWLYEVYKHY-NEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYN 788
            .:|..:.:.| ::.|:||..|...|.|.|:...::..|.:.:...:.|:.|::...|||||||.|
  Rat   196 RFLVMIQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLANSVTPWDILLSLIAAATHDLDHPGVN 260

  Fly   789 NIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDM 853
            ..:.|.....||..|.:.|.|||||...|..||.  |..:|.:...::.:.:...|...|||||:
  Rat   261 QPFLIKTNHYLATLYKNTSVLENHHWRSAVGLLR--ESGLFSHLPLESRHEMEAQIGALILATDI 323

  Fly   854 ARHNEILTQFMEITPIFD--YSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQS 916
            :|.||.|:.|.......|  ..:..|.:|:..:.:|.|||.|..|..::::.|.:::.:|||.|.
  Rat   324 SRQNEYLSLFRSHLDKGDLHLDDGRHRHLVLQMALKCADICNPCRNWELSKQWSEKVTEEFFHQG 388

  Fly   917 AAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELV-PELTELIIIPVRIALEYYRR 980
            ..||...|.|:|..|....|....|:.|:..::.|||....... ..|::.::..|        .
  Rat   389 DIEKKYHLGVSPLCDRQTESIANIQIGFMTYLVEPLFTEWARFSDTRLSQTMLGHV--------G 445

  Fly   981 LNDAQTK--TRKSVADSNTSATSDSNS 1005
            ||.|..|  .|:..:..:.||..:.||
  Rat   446 LNKASWKGLQRQQPSSEDASAAFELNS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:278654	70/230 (30%)
Pde7a	NP_112342.1	PDEase_I	211..431	CDD:395177	69/221 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820