Protein Alignment Pde9 and pde9ab

DIOPT Version :10

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_700447.6
• Gene: pde9ab / 571737
• ZFINID: ZDB-GENE-210629-1
• Length: 518
• Species: Danio rerio
• Alignment Length: 518
• Identity: 196/518 - (37%)
• Similarity: 285/518 - (55%)
• Gaps: 80/518 - (15%)

  Fly   527 IILSKSCSNVD-GDATATAATALSSTVGGGIGGIGGSIKMRASATDIETNALNGARDAIVASNNG 590
            :|.|:.||..| .|...:::....:|....|...|..|.:                |..:.:|..
Zfish    24 VIFSRHCSPCDIRDLLCSSSNIARNTAVLLIDSEGALISI----------------DPTMPANTP 72

  Fly   591 NN-----GNNGNNGNNEYSILQLNNTIIQC------HFNDDDFRALV------------------ 626
            ||     .::.|.|..:..:.|  |.:.|.      .|.:.:.:..|
Zfish    73 NNLYKVMPHSTNQGEEKEDMFQ--NVLSQVAEQFTRAFRNSELKTEVTNRLAMLEKRVELEGLKV 135

  Fly   627 -------KDLKR-KVEYTE---RMNWLCL-----SKRPLGPPHRKSSLPKHQEVKRRFLEICDTT 675
                   .|||: |.|.|.   |:|..|.     ..:.|.|.....:.||:             |
Zfish   136 VEIEKCKNDLKKLKDEMTSGSMRVNCNCKYNFTDDGKKLSPRRDVPNYPKY-------------T 187

  Fly   676 FSEEVRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFH 740
            .|:|...||:.|.||.:.|...:::..::.|:.:||.:::|::...||:.||..:.::|.:.|||
Zfish   188 LSQETIDALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRDNPFH 252

  Fly   741 NFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYND 805
            ||||||||:||||.:.....|..||...:..||:.:.:|||||||||||.||||||||||:||||
Zfish   253 NFRHCFCVSQMMYGMIHLCGLQDRLTMTDMCILMTAAVCHDLDHPGYNNTYQINARTELAVRYND 317

  Fly   806 ISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIF 870
            |||||||||::||::|..||||||.|...::|..||:.||..|||||||:|.|||..|.:....|
Zfish   318 ISPLENHHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMAKHGEILDSFKQKVDNF 382

  Fly   871 DYSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKV 935
            |.:|..|:..|.|:|||..|||||.||.:|||||:|.||:|:|.||..||||||||.||||.|||
Zfish   383 DCTNEEHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 447

  Fly   936 SKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYY---RRLNDAQTKTRKSVADS 995
            :||.:|:.||..||:|:||.:.:|.|::.|:::.|:|.:.::|   ::::||.::.:|...:|
Zfish   448 TKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQIDDAMSEAQKKKTES 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:459723	136/227 (60%)
pde9ab	XP_700447.6	None