Protein Alignment Pde9 and pde9ac

DIOPT Version :9

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_692819.3
• Gene: pde9ac / 564389
• ZFINID: ZDB-GENE-130530-807
• Length: 558
• Species: Danio rerio
• Alignment Length: 457
• Identity: 184/457 - (40%)
• Similarity: 260/457 - (56%)
• Gaps: 73/457 - (15%)

  Fly   597 NNGNNEYSILQLNNTIIQCHFNDDDFRALVKDL-----------KRKVEYTERMNWL-------- 642
            ||.|..|.|:.|:.:  |....:|.|:.::..:           :.|.|.|.|:..|
Zfish   109 NNPNFLYKIIPLSAS--QLGEKEDMFQNVLSQVAEQFSRAFRINELKTEVTNRLAMLEKRVELEG 171

  Fly   643 -----------------------------CLSK-------RPLGPPHRKSSLPKHQEVKRRFLEI 671
                                         |..|       :.|.|.....|.||:
Zfish   172 LKVVEIEKCKNDMRKLRDEMTSRAGARVNCPCKYNFSDDGKKLTPRRDIPSYPKY---------- 226

  Fly   672 CDTTFSEEVRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNE 736
               |.|:|...||:.|.||.:.|...:::..::.|:.:||.:::|:|...||:.||..:.::|..
Zfish   227 ---TLSQETIEALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRS 288

  Fly   737 VPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELAL 801
            .|||||||||||:||||.:....||..:|...:..||:.:.:|||||||||||.||||||||||:
Zfish   289 NPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAV 353

  Fly   802 RYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEI 866
            |||||||||||||::||::|..||||||.|...:.|..||:.||..|||||||||.|||..|...
Zfish   354 RYNDISPLENHHCAVAFQILSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHK 418

  Fly   867 TPIFDYSNRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMD 931
            ...||::|..|:..|.|:|||..|||||.||.:|||||:|.||:|:|.||..||||||||..|||
Zfish   419 VDHFDFTNEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAAFMD 483

  Fly   932 PDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYY---RRLNDAQTKTRKSVA 993
            .:||:||.:|:.||..||:|:||.:.:|.|::.|:::.|:|.:.::|   ::::||.|:.:|...
Zfish   484 REKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQIDDAMTEAQKKKT 548

  Fly   994 DS 995
            :|
Zfish   549 ES 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:278654	135/227 (59%)
pde9ac	XP_692819.3	PDEase_I	291..521	CDD:278654	135/229 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	1	1.000	-	-		FOG0004612
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2223
SonicParanoid	1	1.000	-	-		X3819
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750