Protein Alignment Pde9 and pde6b

DIOPT Version :10

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_073791330.1
• Gene: pde6b / 559332
• ZFINID: ZDB-GENE-090421-2
• Length: 912
• Species: Danio rerio
• Alignment Length: 413
• Identity: 104/413 - (25%)
• Similarity: 182/413 - (44%)
• Gaps: 62/413 - (15%)

  Fly   613 IQCHFNDDDFRALVKDLKRKVEYTERMNWLCLSKRPLGPPHRKSSLPKHQEVKRRFLEICDTTFS 677
            ::|  .||:    ::|:.:..||.:|.                   |:..| :...|||    ..
Zfish   457 VKC--RDDE----IQDILKTREYFDRE-------------------PRDCE-EEELLEI----LK 491

  Fly   678 EEVRAALRLPAFDSYEWSDADVIHLMQT-----MFVELGFIEKFSIPVDTLREWLYEVYKHYNEV 737
            :|:....:...: ::.:||.|...|...     |:.|:|.::||.:|.:.|..::|.|.|.|..:
Zfish   492 KELPGPKKFEIY-AFHFSDFDCTELQLVMCGIQMYYEVGVVKKFQVPQEVLVRFMYSVSKGYRRI 555

  Fly   738 PFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALR 802
            .:||:||.|.|.|.|:.:.....|.....|||.:.::.:...||:||.|.||:||:.::..|| :
Zfish   556 TYHNWRHGFNVGQTMFTLLTTGKLKQYYTDLEVMAMITAGFLHDIDHRGTNNLYQVKSQNPLA-K 619

  Fly   803 YNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEIT 867
            .:..|.||.||......||.....|||:|.:|....::...|...|:|||:|.:.:..|.|.:|.
Zfish   620 LHGSSILERHHLEFGKFLLGEESLNIFQNLNRRQTEHVFHLIDIAIIATDLALYFKKRTMFQKIV 684

  Fly   868 PIFD-YSNR-----------AHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEK 920
            .:.: |..|           ....::..:::...|:|...:|.:|.......:..||:.|...|:
Zfish   685 DLSETYEERKKWIDFMSLETTRKEIVMAMMMTACDLSAITKPWEVQSKVALSVAAEFWEQGDLER 749

  Fly   921 S--EGLPVTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELVPELTELI--IIPVRI-----AL 975
            :  |..|: |.||.:|.:: |..|..||..|...:::......||:..:.  |:..|:     ..
Zfish   750 TVLEQQPI-PMMDRNKAAELPKLQCGFIDFVCTFVYKEFSRFHPEIKPMFDGILNNRMHWKERQE 813

  Fly   976 EYYRRLN--DAQTKTRKSVADSN 996
            ||..:|.  :...|.|:..|..|
Zfish   814 EYEAKLKAMEEAVKARQEAAAKN 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:459723	67/242 (28%)
pde6b	XP_073791330.1	None