Protein Alignment Pde9 and Pde7b

DIOPT Version :10

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_008756813.1
• Gene: Pde7b / 140929
• RGDID: 621016
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 77/269 - (28%)
• Similarity: 130/269 - (48%)
• Gaps: 27/269 - (10%)

  Fly   699 VIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYN-EVPFHNFRHCFCVAQMMYAITRQANLL 762
            ::.|:..:|...|.|..|.:.:.||..:|..|.:.|: ..|:||..|...|.|.|:...::..|.
  Rat   183 LVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLA 247

  Fly   763 SRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECN 827
            |.|..|:.::.|::...||:||||.|..:.|.....||..|.::|.|||||......:|.  |..
  Rat   248 SFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLR--ESR 310

  Fly   828 IFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSNRAHI-------------N 879
            :..:..::...:|.:.:...|||||:.|.||.||:.           :||:             :
  Rat   311 LLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRL-----------KAHLHNKDLRLENIQDRH 364

  Fly   880 LLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRF 944
            .:..|.:|.|||.|..|..::::.|.:|:.:||:.|...|:...|.::|..:..|.|.|..|:.|
  Rat   365 FMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGF 429

  Fly   945 IGLVLLPLF 953
            :..::.|||
  Rat   430 MTYIVEPLF 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:459723	66/228 (29%)
Pde7b	XP_008756813.1	PDEase_I	224..458	CDD:459723	66/228 (29%)