Protein Alignment Pde9 and pde6a

DIOPT Version :9

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_002936750.3
• Gene: pde6a / 100489913
• XenbaseID: XB-GENE-988755
• Length: 866
• Species: Xenopus tropicalis
• Alignment Length: 416
• Identity: 113/416 - (27%)
• Similarity: 187/416 - (44%)
• Gaps: 71/416 - (17%)

  Fly   618 NDDDFRALVKDLKRKVEYTERMNWLCLSKRPLGPPHRKSS------LPKHQEVKRRFLEICDTTF 676
            |.|.:..:.|...||..|.:.:|:           |.|.|      :.|.:|:..|..|.|:
 Frog   433 NTDTYEKMNKLENRKDIYQDMVNY-----------HVKCSNDELQIILKTKEIYNRLPEECE--- 483

  Fly   677 SEEVRAALR--LP---AFDSYE--WSDADVIHLMQT-----MFVELGFIEKFSIPVDTLREWLYE 729
            .||:...|:  ||   ..:.||  :||..|..|...     ::.||..::||.||.:.|..:|:.
 Frog   484 EEELYEILQEELPDPTEAEIYEFHFSDLPVSELFLVKCAIQIYYELEVVDKFHIPQEVLVRFLFS 548

  Fly   730 VYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQIN 794
            |.|.|.::.:||:||.|.|.|.|:.:....||.....|||.:.::.:..|||:||.|.||:||:.
 Frog   549 VSKGYRKITYHNWRHGFNVGQTMFTLLMTGNLKRYYTDLEAMAMVTAAFCHDIDHRGTNNLYQMK 613

  Fly   795 ARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARH--- 856
            :...|| :.:..|.||.||......||:....|||:|.:|..:::....:...|:|||:|.:
 Frog   614 SGHPLA-KLHGSSILERHHLEFGKFLLKDESLNIFQNLNRRQYDHAIHMMDIAIIATDLALYFKK 677

  Fly   857 ----NEILTQFMEITPIFDYS-----NRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEF 912
                .:|:.|....|...|::     .:....::..:::...|:|..|:|.|:.......:..||
 Frog   678 RAMFQKIVDQSQTFTSEKDWTEYMMLEQTRKEIVMAMMMTACDLSAIAKPWDIQSKVALLVAAEF 742

  Fly   913 FAQSAAEKS--EGLPVTPFMDPDKVSK-PGSQVRFIGLVLLPLFEALGELVPELTELIIIPV--- 971
            :.|...|::  :..|: |.||.:|..: |..|..||..|...:::......||     |.|:
 Frog   743 WEQGDLERTVLQQNPI-PMMDRNKADELPKLQCGFIDFVCTFVYKEFSRFHPE-----IQPMYDG 801

  Fly   972 ---------RIALEYYRRLNDAQTKT 988
                     ::|.||     ||:.||
 Frog   802 ILNNKKEWKKLADEY-----DAKMKT 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:278654	67/242 (28%)
pde6a	XP_002936750.3	GAF	73..232	CDD:214500
		GAF	254..441	CDD:214500	2/7 (29%)
		PDEase_I	558..802	CDD:395177	69/250 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D904682at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920